Luận án Nghiên cứu sử dụng thực khuẩn thể trong phòng trị bệnh thối hạt trên lúa do vi khuẩn Burkholderia glumae
- Phân lập được 112 dòng TKT và 60 dòng vi khuẩn gây bệnh thối hạt tại chín tỉnh
đồng bằng sông Cửu Long của Việt Nam.
- Đã chọn được 8 dòng thực khuẩn thể (ФBurTV25a, ФBurDT46, ФBurDT47a,
ФBurDT47b, ФBurDT48a, ФBurVL34, ФBurVL39, ФBurAG58) có phổ kí sinh rộng
trên 75% trong tổng số vi khuẩn gây bệnh thối hạt.
- Xác định 6 dòng vi khuẩn gồm BurVL21, BurDT46, BurDT50, BurDT51,
BurKG52 và BurKG57 mẫn cảm với các dòng thực khuẩn thể phân lập khoảng trên 55%,
đồng thời xác định được 6 dòng vi khuẩn này là loài Burkholderia glumae bằng kỹ thuật
sinh học phân tử với cặp mồi đặc hiệu 1416S/1414A. Trong đó, dòng vi khuẩn BurDT46
được phân lập tại Đồng Tháp gây bệnh thối hạt cao hơn các dòng vi khuẩn còn lại trên
giống lúa OM4900 trong điều kiện nhà lưới
- Tuyển chọn được 4 dòng TKT (ФBurAG58, ФBurDT47a, ФBurDT48a,
ФBurVL34) có khả năng phân giải B. glumae DT46 gây hại cao nhất.
- Bốn dòng TKT đơn (ФBurVL 34, ФBurAG58, ФBurDT47a và ФBurDT48a) cũng
như hỗn hợp 4 dòng TKT đều cho hiệu quả giảm bệnh thối hạt trên 31% ở điều kiện nhà
lưới. Trong đó, dòng TKT ФBurAG58 cho hiệu quả giảm bệnh cao trên 70% khác biệt so với
các nghiệm thức còn lại. Ngoài ra mật số TKT ở 108 pfu/ml với thời điểm áp dụng TKT 2 giờ
trước khi lây bệnh hay phun TKT kết hợp 2 giờ trước khi lây bệnh và 5 ngày sau khi lây
bệnh cho hiệu quả giảm bệnh cao.
- Về hình thái của cả 3 dòng TKT (ФBurVL 34, ФBurAG58 và ФBurDT47a) dưới
kính hiển vi điện tử (TEM) có đầu là khối đa diện và đuôi ngắn thuộc họ Podoviridae. Kết
quả giải trình tự toàn bộ genome xác định được 3 dòng TKT đều thuộc nhóm TKT độc
mang tính an toàn khi ứng dụng phòng trị ở điều kiện ngoài đồng.
229 trang |
Chia sẻ: huydang97 | Ngày: 27/12/2022 | Lượt xem: 379 | Lượt tải: 1
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TCATTGCAATCTTACTCGTGCTGTACGCAATCGCTGACGTGCTGTGTCGCGTGAGCGATAGGCGCAACACGCGCTGGAGTGTCCAGGTTAT
TTGGGACGGCGATTCGTACCGCCATGCCGCGAAGTCTTACGACGATGCGTTAGCGTGGTTGGCCTGCTACCGTTTCGGCGAGGCATTCATCGATCGCACGTTTCACGGCACTACTGAGTGCGTGGCGCGGCGCATCGCCTACTGACAATTT
CAAACGCGCAAACTACAGGAAAGACCATGCGTGCCTACAATTCGTACAGCCAAGTTGCATTCGACGCGAAAAAGTTCAACATGTGCGTAGCGCATTTCCGCGAGGTGATGCCCACACTGCGTGAGCAGTTCAATTTCGACACGATCGTCAT
CACCGGCAAGTCCGGCGCGTCGCTGGGGTTTGCAGTTGCAGCAGCGTGCGGCCTTCATGTCGTGTACGTTCGAAAGGAAAAGACCGCGCCGAAGCAAAAGGCGTTCTCGCTTATCACCAGCCAAGCCGAGCTTAACGCGGCCATCAAGTC
GATCGGCACTCGCTCCGCACGGCTTGACGCGGACATCCACCGCGCCGCAGTGAGCGTGATCGTACACAGCGCCAAGCACAACGATCCGGACGTGGCAAAGCGGCTGCTGGACGCGATGGGCAAGACGATGCGCAAGTCGGCCATGACC
GCATGGCTGTGCGCATACGGCGCGTTCGCAACCGACGAGCATGGCGCGCTGGTGTACGTGAAGGAGAAGCGTGAGACGGTGCAGACTGAGGCCAACGTTCACGCCGCGATTGCCGAGCCGTTTTGGATGTTCGCGCCGGAACCGAAGT
ACGTGCAGTTCGATCTCCAGAAGTCGGTGGCGGCACTCCTGCGCCGCGCTGAGAATGCCCTGGCGAACGAAGCACAGGACGCTACGCTTATTAAGCCCGATGTCCTCGCCGAGCTGCGCAAACTGGTCCCGGCGGACGCCAAGTAACCGA
GCGTCGATCATGTACATCCTGTACGTATGGCTGATCGGCTCGTTAATGATTGGCGAGCCAGTGACGCCTGAGCAGTGCGAGGCGCAAGCCATCGCGGCCCGGCAACAGCACGGAGTGCGTAATGTCGAGTGCGTTCGACCGCTTCTTGAT
GCCATTGTGGATCTTGGTGCCCGGCTGCGTCCAGTTAGCCAGGGCATGGCAGGCGCTACGCGACTTGCCTGCGTTGAGCAAGCGCACGTGTGACGGCACCGCGCCTGAGCGCAGTACGCACATGCCGTCCTTTACGCCCTTGCGACCGGG
ACCGACGTTGTATGTGAAGTCGGTCCATGCCGCCCACTCGCCCTCTGTCATCGGAACCTTGACACAACTTGCGACGACGCGCATGGCGTCAGCCATAGCCTTCTGCTCAGCAGCGTCGCACTGTGCCTTAGTCGCTACTCCGCGCTTCGCCA
GCTCGCCCGTTATCCCGCGACAGATCGTGGGGACTCCCAACGGGTCGAGATAAGTGCGCGTCACTTGCGGCCCCTCGAACTGCGTAGCGAGCTGAAATGCGCCGCCCAATCCAAGCAAGGACGCTAGCGCTGTTGCCGCTGTGATCTTCTT
CATTACGTTTGCCTCCGAGGTTGTTGCGCAGCAGGAAGTAGAGCTGCGCCAGCAGTACGATGATGGACATCAGTGCCGCCCACTGTGCAAGTGCCGCGCTTCTTGATGCCATTGTGAATCTTGGTGCCCGGCTGCGTCCAGTTAGCCAGGG
CATGGCAGGCGCTACGCGACTTGCCCGCGTTGAGCAAGCGCACATGTGACGGCACCGCGCCTGAGCGCAGTACGCACATGCCGTCCTTTACGCCCTTACGACCGGGACCGACGTTGTACGTGAAGTCAGTCCATGCAGCCCACTCGCCCTC
AGTCATTGGAACCTTGACACAACTTGCGACGACTCGCATAGCTTCAGCCATAGCCTTCTGCTCCGCAGCATCGCACTGTGCCTTAGTCGCCACTCCGCGCTTCGCCAGCTCGCCCGTGATCCCGCGACAGATCGTGGGGACTCCCAACGGGT
CTAGATAAGTACGCGTCACTTGCGGCCCCTCGAACTGCGTAGCGAGCTGAAATGCGCCGCCCAATCCAAGCAAGGACGCTAGCGCGGTTGCCGCTGTGATCTTCTTCATTACGTTTGCCTCCGAGGTTGTTGCGCAGCAGGAAGTAGAGCT
GCACCAGCAGTACGATGATGGACAGCAGTGCTGCCCACTGTGCAAGTGCTCACTTCCTTCGTTGCCATGATGATTCTCCTGTTCAGGTCAGGGTGATTACTGCTCGTAAATGCAAGTGCGGTAGCTGCGACGGTAACGTCCTTCGGTACGG
ATAACCGACGAACTGATACCATCACACTGGTCAAACCGAGTGTCAAACTCAGCCTTAGACACGCGGCTGAAAACGTCACATTTCTTGACGTAGTAGGTGCGCTTACCGGTGGCCAGATTCTCAACGTCCATAAGTTCGGTCTGGTAAAGCAT
GATGATTCTCCTACGTTGTAATTCGGTGGCACTATCGAGGTTCGCGGCCCGCGTCTCTGCCCGTCCTGGCGTATGCGCCCAGGGCATTGCGTTGCACTCCGCTACTGCTACGCCAAGTGCCACCGAATTACAACACCTCTTGCGAGGTGAGG
TTTCGTAGCTTGCTCGCTTTAACAGGGCACCATTCACTACCCATCGCCTCGACGTTCGGGCCGAGCAGTCGGCCGTGTTCCCATGCTGGTTCACGCACACGGATGGGCACGGCGGCAATGGCATCCTGATCGAGATCGAATGCCACCACGTT
GATGCGATGTCGTGCGCCGTACTGCGCCAGTGGCCGTGTGTCCTCCACCACGAGTACCGCGCAAGGTTCGCCTGTCGCGGGGCACTGTTGCGCACCGTTGTACTGTCGGATGTCGAACCCAGCGCCGCGTACCACTCGCTGGATTCGGTCG
TCCTCTATGACGGTGCCTGCGGGCTGGCCTGCCGACTTGCTCGGCCGCTTACCGATGTTGAGAATGTAGATCATAGAGCACCTGTGCGCTTATCGTTGCGCGCCGTGTTGCGGTCCGCTTGGCGGGCTCGTTTCTCCAGTTTGCGCAGTTGA
GCGTTCGGGCCGAGCAGTCGGCCGTGTTCCCATGCTGGTTCACGCACACGGATGGGCACGGCGGCAATGGCATCCTGATCGAGATCGAATGCCGCCACGTTGATGCGATGTCGTGCGCCGTACTGCGCCAGTGGCCGTGTGTCCTCCACC
ACGAGAACAGCGCAGGGTTCGCCTGTCGCGGGGCACTGTTGCGCACCGTTGTACTGTCGGATGTCGAACCCAGCACCGCGTACCACTCGCTGGATTCGGTCGTCCTCTATGACGGTGCCTGCGGGCTGGCCTGCCGACTTGCTCGGCCTCT
TGCCGATGTTGAGAATGTAGATCATAGAGTGCCCATGCGCTTATCGTTGCGCGCCGTGTTGCGGTCCGTTTGGCGGGCTCGTTTCTCCAGCTTGCGCAATTGCAAGGGCGAGTCGTCGCACGGCGACTACATTGAGGGTGACGGCCACGA
GTTTGAGAACTACGCGTTCTTCGATGACTTCGTGAGCAGTGGCGAAACTCGCAAGCGCGTGATTTATGAGCTTGAGGACTGGGCCTTAGAAAGATGCGAATACGCTAATGCGCCTAAGTGCGTTCTCACCATTGAGTACGACGGGGAGCC
GGACACTGCTAGGCTTATCTGCCGCAAGACGCCAGGGGTTGACGGCCCGAGATACACCGGCGGTATGTACTGGTAGGAGGATACATGCAAAGCAACAACACGATCGAACGCGTTCGAAAGCAACGCCTGGAGCAGACGGAAGGGCAAG
CGCTGCG
ФBurDT47a
TTCACCACCTTACCGCTAGCGTCGTCGTAAGGGGTATCCCGCACGTCCTCATGCGCTACGAGATCGTTACGCCACTGGAGCATGAGCGGATTACCCACACCTGCCGAGTTATCGCCGTTGTACTGTACCGGTACGCCGGTAGTACCCTTAGC
CTGCACACCTGGACCATTAGTGCGATTGAACTCGTCAGTAATACGATCCTGCTTTGCTTGAACTGCCTGGGCTATAGACTTCGGATCGAACACACCACCGGGTTTCACTAACTCACCATTCTTCCCGAACTCCTGCCACTGAAGCTGCCCATC
GCCTGTTGCTTTGTAGACCACACGGTTTCCGTCCCCCGGCTTATGCAGCTCGTTAAGCGTAGCCGCGATGGTCTGCGGTCCCACCGAAGGATTGACGCCGAAGTAGGACTGCATGGAGACGCCTGATGGTAGGCGAGGAATCACCAGCGG
TCCGCCATCAAGATCGAGCGTTCGGCCTGCAACCTTGGCCAGCGCCAGCTTGCGTCGAGTGTCATCCGACGCATACGGATCACTACGTGAAATGTAATTCAACTCTTCCACCAGCGCTACCTTGGCCGGAGCTAGGGCAGCGTTCACACGCT
CGTCGTTCTCGAAAAATCCTTGATACGTGCGCAGCTTGTTTTTATCGATGTTAGACTGCGGGCGCAGGAAGTCAGGCACCGCATTGGCAATGCTACCCCACAGACCGCGTGGCGTGATCTCAGCGAGCACAGCAGCATCGGCCTTAGCGTG
GTTTGCGGCTAGCACATTTCGCTGCTCGATCGTGAGCTGAGACTGCTTGGCGAACGTATCTGCTGCGGTCTGCGCTGCGACCATCGGATCATCACCTGCCTGCAACCGCTCACGGAACAGCATGATCTTCGAACGCTCGTCATCCTTAAATG
ACGATAGGTACGCGCCCAGCGCATTGGCTTTGCCCGCGCCTTGGGCAGTGTCGAGAGTCGTGAGGACCGTCTTGAGCATGTTCAACTGCCCTTGATCGATGTTGTTGCCCATGCCGATCATCGACACTGCCGATCGAGTCAAGTCTCCTACG
CCCTTGAATGCAGAACCTTGGCCTGTCTTTACGCCGATTTGTAAAAGCTGTGCTACGGTCGTTGCTGGGTCAACGTTATTACGGGCTTGTACTTGGATGAATGCTTGGTAACCCTGGTCCTCGACCTTGCCCATGGCGAACATAGCTTTCACG
TTGCCGGTTACGTATGCTTGCGCAAGGTTTGCTGAAGCGACCTTCTTCTCGTTGCCCTCGGCCCATGCCTTTGTCAGTGATGTGATGTCCCCGCTTTGGATGGCACCGATCTGCACGCCCTTCGCCACGAAGGCTTGGAACTGATCGTAGGGC
ATGGCCGGCGTCAGCGGGTCTTGAAACTGTGCCTCCATGAGGCCACGCTGTGCGTTGTAGTTCGCGAGCCGCATCGTGCTCGTGTCCTTGCGCGACTGCTCATACGCCTTTGACAGCGCAGTCTGATCCTCGAATCCAAGTTGGTCGAGCA
GCGTGCCGCCGCCGGGCAGCTTCGTGTCCCGCGCCTTCTCGTACAGAACTTCGTTGTTGTTCTGGAGCGCGAGCGACAGCGCCTGTGTGGTGAGCTTCTGGCGGTTCTCTGGCGGCAAGTTAGGATTCGACCACACGTTGCTGTACAGCCC
TGCGAACGCGTCATCCGCCGCAGCGTTGTACGCAACCGGGTCGGTCTTCGCGTTGTTGAGCGCGTCAAGCCGCACGCTAAGGTCCGTCTGTACACCCTTGCCGATCTGGTCGATGATGAACTTCGTGTGCTCTACAGCGTGCTTAGCGATG
GCCGATCGATCGCTGGTGAGCTGCTGCGCGATCAGCCCTTTCCGGGCATCCAGCGACATGCCCTGCATGTTGTCCAGCACCTTCTGCCGACGCTCGGCGAGGTACTGCTTGAACTGCTCGGGAGACTGCTCCCGCAAGGTCTTCATGTCGG
CGGCGGTCTGTGCTTCCGCGTCTGCTTGTGCGAGACGCGCCCGCGTGTCCGCCCAACCCGCACCGGTCCAGTTCTTGGTGATCGGGTTGCTGTCGATTGCAGCCTGCGCATCGTCGCTGCCAGCCGCTGCCGCTCCGCGCAAGTACGCTTCC
TCGCGCTCGTTACCTACCTCCTGCTGTGCGAGCTGGGTGACGGGCTTCGTGAACGTATTCAGTACGTTGTCGAGGATGCCCGTCATCACCGAAGGCTGTGGAGTTGAGGGGTCATAGAACTTACCGGGATCGGCCCGCACAAATCCTACGT
TACCAGGGACAGCGCCCGCTTGAGGCGCACTGCCAAAATCTATGCTTTGCGCATCGCGCTGAACTGCCATGTTTCCTCCTTAGCTGAATGAGTACCCAGGCCCAGACAAGATGGACTTATAGGAATACGAACCTGCATCGCTCTTGGGCGT
GTTGGTCGGACCAAGCGAAAGTTTATCGCCCGCGTAGAGCTGCAACGCGGCCCCACCGGCTTGGGTAAGGCCGGACAGCAACGATGCGCCAAAGCTCTGCGTAGGCATGTTGGTGTTGTACTGCCGAGCGGCCTGTAGTGAGTCCTTACC
GGACATGGCGGTCTGCTCGATCGCAATCTGTGCGTTCTCCAGTGTCTGCGAGAAACTTTCGTCAAGGCCGATTTGTGCCTCGTCTTGCTTCTTCTGGATGTCGCTAACAGTAGCATCCACCGACGCGCCCACAGTACCAGACGCCGCCGCATT
CGCTACGGCATTGCCCACAGCAGCCACGCCCTTGCTGGAGATTGACTCGCTTTGCTCGGCTGCTGCTGCACGCTGCCGAGCAAGCTGTAGGTTCTGAATACCGACCATGTAACCGGTACGGATCATGTTCGCGGTGTTGGCCTCCGCAATCG
CCTGATTCTGAGCTGTGACTGCCTTCACGCCTTGGGTGTACTGGTCGAGCGCAGCGCTCTGCTGCTTGCTCGACCCGAGTAACCCGCTTGCGAAGTTCAGCCCCAGCGATGCAAGCTGGAACGTACCAAGCATTAGCGCCTCCGAAGTTTCT
GGTTGTAGCGGTTGGTTGTTTCTACTGCCACGATGTTTAGCTCGCCAAGGCCATCCGTCGATAGCACAAGCGTAGTGCTTGCCGCTGCTGTACGACATGGGATGATCGTAGTAGCGTCAACCGTAGCCCGACGCCGGCCAAGGCCAAGCTC
AGGGCTCGACCAGTACACTGGGCCTACGTCTATATCAGTGTTGTCGGAATCACTGGCTGCATCGCTAACCAACGCGTTGAACTCTGACGAGTTAGCAGTGCCGATCATGTAGCGCAGGATAGTCAGCTTATTGCTGCTGATTACGACGCCAT
TCTGATCCTTCACCATTGGCGTAGTTGGACTGAACGATGAGGTGAACTTGATGCCCGCTGCAACATTGCCAGTTGGGTATGAGTCACCTGTGGTAAGCACGCTGGAAGTGTGCGACTCGATGCCAACCTCTTCGCCACCGTCGCTAGACTG
ATCTGCCAATGACAGCCGATCAGCAATGTTCGGGTCAAAGATCAAGTGCCCCGGCGGGACAGGTGCCTCGTGATCCGTTACCGTCGTGTTGGTGTACAGGTCGAGGAACGGTCGGCGGTCGCTCGCCGCATCTAGCGTACCTACGCGAGG
GTCGATCGTAGCCACGAGAACATTGGTCCCATTCACGAACAGCAGGTTAATCTCGCTACCTGTAAAGAAGGCATCTGCGATGTCGTACGGGAACGTCCAACGGTGCCAAGCTTGCTGCACTTTATCTGCACCGCTCCACAGGTACTCATGAA
CAATGAGCTGCCGATGGTCGGTTGTGCTCGCAAAACACGCGATGTTAGCCACCGACGATGACACAGCAAAGCGGCAACGCCCCGGTAGGTACTTGGGTAGGTGCCCAGTTACGTCGGTTGACACGTACTGCGAGTCGGTGTATTGCGACG
GCACCATTTCTAGCATACCGTAAAACTGCGTGTTACGTGGCGCAGGGTACATCAAGGTCCGCCCTAGCGTCACCGGCGAGCAAGTCATGTCACCTTCGTACGAAGAGGTGACTACCACCGTCGCGTTTGACGGCGTAATGGCAACATTCCC
ACCGGGCACAACTGCTTGGTACTTCTGACTGAACAGCAGCAAGTCTTTCTGGAACGGGACAGCATACCGATAAGCCGACGAGGAGTTAGCCGATGCCGCCACCTCAATCGGATCGCTTGCCACCACAGAGGTAACCGTCGAGCGGAAGAA
CCGGCGTGTGTTGATGCTTGCGCTCATGTTGATACTCGGCCCGCTCAGTATCACCAGACGGCCCTGGTAGCTGCCTATACCAGTGATACCATTCGTGACGAAGTACGGCAGCGGGTTACTGTCATCGTCGCCTGCGTATCGCCCTTCGTACG
TCTGGTCGTACTCGAATGCCGTACCGGCGCTGTTTAGGGTTAGGCGCAAGGGCATGTTGGCTAGTGCTGTTGGTGAACCGTACTGGCCCACTTCCGCCCACGCCTGTTTCGCGAAGGTGTACTTGTAGTACGTCGGGAACGCTGTACTGCC
TACCGCGATAACCAGACCATCTGCCTGTGACGGCAGACGCGACGGCAGATCGCCAGACGTAGGCACGTTGCCCTGCCCCGACACGCCGACGTACGACGTGGAGGTGGCCGTGCCCACCGTCATACCATCACGCGGGCCGTGGATCGATAC
GAACGAGCCATACCAGTACGCAGTCCACCCTGTGGTGGCCGTGTCCGCATTGATAAGTGCCACGAGCTGTCCTGCGATCGCCTCAGGCGTAGACGCATTATCGGCCCCGGTAGCAGTTGCTGGCGGCGTGGTCGTTTCGTATGTACGCGCG
GCGAAAGCTGAGTCTGCCACGAGAACAGTGTACTGTTTCGAGAATGCTCCGGTCTTGATGTAGTAGAAGCCGACACGGCTAGGACTAGGCCCAGCGGCCCCGTACAAAGGTACAGGCGTGTGCTCTAGGTTAGCGAGGAACAGATCAGG
CCCAACACTCGTCATGCGAATCGCGTTACGACCGCTGGGCGTCTGCAAGTAGGGATTGGCCGGCAGTGTTTGAATGGGTGCCCAGGCTTCCGTGTACAGGCGCAGCACCCCATCAGCCGTATTCAACACACCACGTACACGTGAGCCGGC
AAGGTCTGCATCGAAACCAAGCACACTCTCGACGGAAGTACCAACGGTGCCGAGTTGTAGGAGCTGCCGAGCCCATGCACCTGGACGGCGACGCAGCCCGGTGACGACATCCGACAGCATGTTCTCTTGCGCGCTAACTTGACCGTCGAG
CCGTTCGCGCGCAATCTGCTGGCTCACGCCTTGAATCTGAGACTTCTGCGAAGACTCGAATGCAGCCATGGTTACCCCCTCATAGCGTTGCGCAGCTTCCGGTAGCGCCGGGACTGCTTGATTGTGTAGCGCATCTGGCGCAGATGCTCTTG
CTCCATGTTGCCCCGCGCGATCGACGCGTAGGACTGCCAGAGCTGTACGGTTTGCTCAAGCCCGATGTCGGTCACGTAGATGGCGACCAGCGCCGAGAACAGGACGTACTTTGCAGCGGACTCGGGCAGGTCGTTGAACTCCCAGCGTTG
AATGAGCTTGCCCTTGATCTTCGACGGGAACACGTAGCTACGGGTTCGCTGATTGTAAAAGCGTTCACCGCGTGCCGTCACGATGCCGTACTCGGGCTCCGCGACAAACGACAGCGTATCCTCCGGCACATCGATGTAGCCGTTCGGATCA
GGAAACAGCTCGACGTGGTGATACGTGTTGAACCACCAGCCGGGTTGCAGCAGCAGATCGATCTCAGAGTCGATCTGCGGAAGAATTACCGCGAGCGTAGGAGACTTCGATTCCAGCGATGTCACCGGATGTTCTCCTAGCTTCGGCAGA
ATTTCGTTGACAGCCGTTAGCAAGTCCATGGAATCCCCTATGGTCGAGACAAAAAAAAAAGCCCCGCAACCCTGTTAAGGATCGCGGGGCTGGGCGAACTAAGCGGCGGATTCCTGCTCCACCGCCGACGAACCTACGTCTTTCGATTAGT
CGCTGAAGATGACGCCAACGGCGTCCGGTCGCTTCTGGCCGACCGTGTACATTTGGAACGAGTCCAGGTACGATTGGAACTCCTTCGGGTACTCCCACACTTTGACCGTCATGCCTTGGGCTTGCACGGTCACGAGTGCCTTCTGCGGGAA
GAACACGATCAGCAGCGCCTTGGCCTCTGCGGCCGACACGTCGAAAGCCGAGCCCAGCGGGTGCGACACACCGGCGGTCGGGAAGATCGGAGCCTCGATCACGCGCACGCCATTCAGGACCGCGATGCGGCGCTGGGCGTAGTCGTTC
GACGCCGAGCTGCCTTGGAAGTCCACGTTCATCAGCTTCTTGTGCTCCAGCAGCACGTTGAACGCGTCCGGATGGATCAGCGTCACGGTCTGCGCGAGGCCCGCACCGAGGCGGCGCTTCACGAACTCAGTCAGCACTTCCTTGTGGTTCT
GGACGATGATGTCGGCTGCTTTCTCGAAGCCGGTGAGATCGCGGCCGACTTCCACGACATCGCTGCCGATCGCGAGTGCGGCTTGGTAGCCCGTCATGACAGCGCTGATGCCCGGATGGAATGCGCCAGCCAGCGAGGCCGGCGGAACG
TACGCCGCGCACTTGATGAGCTGAATCACGTGGGCCTCGTCAAACGAGATAGCGTGTGCCGATGCGTGCTCGGCGGCGTACTCGCTCTTGAAGTCCGGCGAGGTCCAGTCGTCTTGCCAGTCGAACGGCGTGCGGATGTAGCACGTGGTA
TCGACCGTCACGATGAACTTCTCGTTTGCGATGCGAGCCGAGTCAAGCGTCTCGCCCGAGCGGCGACCCTTCACAGCAGCCGCGCCGATGCGGTCGCCGCGCCACGTGTTGGTTTGGTTCTGCACCGATTTGTAGTTCGTGAGGCCCGAGG
CGCGGAACAGCGACTCAGCGCGGAACGAACCTTCAATGTCGCCCTCGTACGCTTCAATGTGGATGTCTGCGTCCGCATCGCTACCGGCCCACCAAGTGCGGGTCAGTTGACCCTTGTTATCTACGTCTGCCATTAATCCTCCTTGTGGTTAG
GGCTTACAGGCCCATGTTCTTGCCAAGCTGTCGGCGCGCGGTAAGCTCACGTTCACGGTCGGCAAAGTCCGACGCGTTGCGGTTGAGCTTAAGACGCTCCGCTTGATACTGCTCCTTGGACAGCCCAATGGTGCCGTCAGGTGCCCCACCG
CCAGCGGCGACGTGGCCTAGGGGATCGCGCGGAAGCGATCCCGATTGCTTCGCGAAGTCGAGTAGCGCAGCACTTGCGCTCTTGATCTTCGCGGGGTCCATGGAGTTGAGGCCATGGCCTACGAACTCCTTGAGGTATGCCGGTGCCTTT
GCGTTGAATACCGCCACGGACGCCTTCCAACCAGCCGCCCCACCGGCCATGTCCTCGATGGATTTAATCAGCAGTTCCGACTGCGCGTTGATGTGGTTGACAAGATTCTTGGCAACCGTAATCAGGTGATCGGCCTTATCGCCGCCTACTTC
CTTGAGGTACGCTTCGTCAACAAGGCCCGCGTCGGCTCGTGCGATGGCCGTGCTCACTGCACGGTTCACGTCGAGGTTCGGCGCGGCCAGCGAGAACAGCGAAAGCGCGCTAGTGACTACCGGGTCGTTCTTGCCCGCCTCGCGAACGGC
CGTAAGCGTCTGGTCATCTTGGATAACAGGCACCGGTTGCGCAGCGGCCGTGTCGTCCACTTTACCCGGAGTCGGTGCAGCAGCTTGCGCCTTCTTCCACGCTTGGAATGCTGCATACTCGGGATCAGCATCCGGGCCTGCGGGCACTGGT
TCCGCACCGGGTGCCGGCGGGAGGTTGGACGGCGCTGCGTCGTTGCGTTGCTGGTTCGACGGCGGCACTGGGGGAATCGGAGCCGGCGTGCGGTCACGACTGCCCAGCGTCACTGCGTCAGCCGGTACAGCTTTGGACGGATCGAAAC
CGGCGGGGACTGCGACTTGCTCTGCCATTGTGTGGCCTCCTTAGTTGTTGGCACCGGGCAGCGAGCCGATGGCTGCTGTCTGTGCTGCGGATTGGGTAGCGGCGAGTTGAGTCTGCGCCTGCTGCATCTGTTGCTTGGCCGCATCGAACTT
GGCCTGGGCTTCCTTGTCGCGCAGGATGGTCGTAGTATCGACAGAGGCACCTGCGTAGATAACATCCATCAGCTTGCGTGGGTCCACGCGATCATCGATCGACGTGAGGGCGTTAGCGATGGCTGCTGCGTCCTGGGCGGCTTGGAGTAT
GTTCTGCACGTCGATGCCGCGACTGAGGGCGGGAATACCGGCGATCACGTCAAGCACCAACGTATTCGACAGGATACCTTCCAACGCGTCTGGCTTCTCTTCCACCACCAGCACGTGGGCCAGCGGAACTTGGAATGACTCAGCCAGTGC
GCTGTACTGCCCACCAAGAGCTTGGTTAGCCTCTGCTGCCTGCTGGCGCAGTTCGTATGCAGTGACGCGTTCAGCGTCCCGCACATTGGCCGTGTACATGAAGGCCCGCGACAGATTCGTGAACGTCGAGGAGATCAACTCCATCATCGCT
TGAATCTTCTTCGCGTCGCCGGACTCCTGCACTTGGATCGAGCCCTGCGTGCCCTGCACGTATTCGCCAGTCTCAGCGTTGTTCAGATCGTCAACGTCGTTGCCACTGCCGGGCTGTACGAGGTTGAGGAACTTCATGGCCGAGATACCATA
GAGCGCTAGCGCTTCCGACTCATCGCTGATTTTGGCGAAACCTCCGGCGTAGTCCTCGACCAGTCCTCGGCCGTAGTGCTCGCCAGGAATTAAGGACCACGTAGGCGCTTGCCAGGGGCAGAGGTGCGCAGGGTACTCACCGGGTGTACC
TATCGGCATGCACTCGATCTCTTGCGACACGACGTACTTCACGTCGCCGCTGTCCATCGTTACGCGCTGAATGCGAGTGTACACCTCGACGTTCGTTTCGAACTTGTCCATGCGGTACTTGTTCGGGAACCGCGTAGCGAGCATTACCTGAAT
CTCACGCGACAACCCGGCGAACGATTCGAACTCACGCAGAATGCAGTCGGCCAGCTCACCTGTGCCGGTGCGCCGGCACGAGAACGACTGAAGGCCGTACGTGATCGTGCGCTTAAGTTTCGAGTCTCGCTTCGTCAGGCAGTTGCCCGT
TACGATCAAATGCAGGATTGCCAGCGTGAGCTGGTTGTAGCTGGAGTTCAGGAACACCCGTTGCGAGGCGTCCATTTCGAGCTGCGCCAGGGCCGACTGAAACTCGCTCATGTCGATGCCCTTAGCCTTGGCGTGCTCCTTGAGCTGCTTG
CTCGGCTTGATACCGAAGAATGCGCGGTTCACCGGGAACAGAAGACCCGCGAGCTTGCTGCCGAGGTTGTTCACGAGAAGCGCGCCAATCTCCTGGTAGTCTCGCTCGATCACTTCAGCGGTCCCACGATGACAGAGTTCCGCCATGAGTT
TCGGCAGTGTCCAGTGCGCGTACTGCCGGCACTTGAGGATCACTGAGTCATCCCGGTACTTCTCGAACAACGACTTGTAAGACTGGTTGCCTACCATGTGCCCTCCCTTAGACGTTGACGCCCAAGGTCGAAGCAAGACCTTGCGACGCATT
GCGCCGCTTGGTCAATGTGTCAGCAGCAGCAGCCGTACCGCCGGCGGTTACCGTCGCGGCTTGGGTTGCGTCTGCGTTGTTCGCCAGTGCGGCGAGGTTCGCGTTATAGGTTGCGGTCTGCTCGGCGATCTGCTGCTGAATCTGGTTCGCT
TGATCTTGAGCCTGCTGTGCTCGTTTGGCGGCACCGCTGTCCGTGAGCCCGATTGTGTCGGTAACCCATGAGACTACCTTGCCCATGTCTACACCTCCAGGAAATACGATTCGTTATGAGGCCGGAACCCTGCCCTCATGTAGAGGCGTCGT
AGTCCGGGACGCAGAACACCGTTGCCTGTTTCGATCCCGACGCAGGAATGAACCCGTGCCAAAATCTTGAGCGCTTCGGTGTACGTGGAGAAATTGCGAGTAGGCGCTACGCCGATCACTAGCAACTCAGCAAGGTACTTGTTCGGGTTG
CACCACGACGCACCAGCGCTGTACAGCACCAGCCAGTCGCGGTCATTGATCCAGACCGCGTGGATCGTGCCGCCTTCGATCTGGCGCAAGGTCCACGCAACGTCAGCACCTTGTGCCATGTGGTGATCCTTGTTGCGTCCTAGATGCGCAG
TCAGCTCAGAGTGTGCACTTTCCCAATCTTGCATCGCCCACGCCTTGTTATGAAGAATCCTCACTTCGGCACCCGCTCACGAATCCAGGTAATCACCGATCGTTGTCCTAGTCGTTGGCGCAGTGCTGCTTCTGTGAGATTTTCTGCAAACACC
AACTCGGGGAAGCACCGCTCCAAAGCATCGAGTTGCTGCTGCGTGAAGGTTACCTTGCTCGGATCGACGGGACGTGCCGGAGCAAAGCCGGCGCTATGTACGGTTTCAGCCATGTAGGTATCTCCAATCTGGGGCATTCTAAATTAGGCTT
ACCGACAACATGGTAAGGCTTATGTACTACACTAGATACATAATACTGTTACTCTATACTATCTAACTATTGTAACCGCTATGTACTGTGTCTTGCTCGCGAGGTCGGTCCTATCGAACCTCCCCGCTCGCGCTTTGTTTGCGCTTTCCACCGTG
TGGCACTCTAAACTAACAGAAGAAGAACTCACTAGTAAGTACATCTGAGAGGTTAAGATCACCACGCTTAGGGAACTCTCCTGTAGCTCCTACCTCCCACAAGAAGTCACCTAGTACATCATGTTCTGCATACATACGTACAAATTCCTCACG
CAGTATCCTGTGCATACTACTTACAGAACTAGGGTGTGTACCAAACGAATCATGGATACCTACGAAGGCGTGCCCCTGCTTCTTCATTGCTAAGGCAGTGAACGTCAGATGACTAGCATCTAATGCATGCACGAAGTTCGGCGCTATTGCGT
TCTGCATCTTCGAAGGATTAACCCCATCGCGTTCCTCGTACATTGTGATACGCTCCACTCCGCAGCTAGACAAGCGTACTCGCATGAGTTCCACCTCAGGGTAGTCATGTTGCACCTTGAAGCCCGTCGGCGTTGTCCACTCCATGCGTGAGC
CTTTGGGTACTGTACGTGTGGCCTCCTTAAGCCAGCGCATTGCTTCCGCTGCTGCCGGCACTGCGTACTCGATCCCGGCAAACAGCGCTTTCGCACCGTAGGTACTCAGGTCGATGTTGCGCTGGCCTTCCTCCTTCGTGTCCTCTCGTCCGT
GCAGCACCTCACCTTCAAGAAACTCTGCCGTACCGCGCAGCGTCGCGCCATACACATACGTCATGACGGGCTTCTTTGCCCAGTCACGCTGAATCTCGTGCGCCAGCCAGAAGTCCCGAGCAGGGCTAGGCTTGTCGCGCCTGATCGACTCC
ATGGCCCCACTCCCAACGTGGCGGTAAATGTCCTGCTTCTCATCGCCGCCGGCATCGAACAGGTTCACGTACTTGCCGCCTGTCGAGTCGCGCAGCATGGCGCTGAAGTGTTGGAGGCCCGAGCACGTCGCGTCCATGTGGATCGGGATGC
CCGTCTCGTACAGCTCAGGGTTCCGACAGCGCAATGCCTCCCGCAGCTCGTATGCGGCCGCATAGGCGCACCATGGGCTGTCTTTACCCCACACCCCAGGACAGTCCTCCGGGGCGTCCAGAGACGCCTCCAGGCGCTTCCAAATCGATTCT
ACGTAGGCGACCTTCAAATGCGGCCGGGCCTTGTCGTAGCCGAGCGAGTTCGCAATGTGAACACGGAGCCAGAACAGCCCGTCGCGGCCCAGCGGCCGGCGCTCGTGGAAGTGCAGCGCAGCCTTCGCCACGTCGCTGCCCTGGGGATT
CGGCGTGCCATTGTAATACCAGCGGCCTCGGGTATCCATCATCACCGGGAACCAGATCGGCTGGCCTTGCCGCTTGGCGAGCTTCAGGAAGCCCGCGATCTCCAGTACGTGGCCCTTCCACTCCTTCAGGCCGGTGTAATACGCGGTTGCTT
CCCGCTTCCACCGCGTAAATGCCTCCAGCTCGGCCTCAGATGCGTCGGCCTTCACCCAGGTATCCGGGAATGGAAACAGCGGCTTGGCGGGCTTCTCACGGCGCGGCAGGCCCATCGTGGCACCGCCCGCATCCCAGGCCCGCCGCACGG
CTCGCAGGGTCGGCTCGTGCACTTGGAACGCCTGCCCCTGGAGAAAGTTCGCGCACTCGAACACGAGCGGCATCTTCTCTGCCGTGAACTGTGCGCGGATGCGCTTCCGCTGAGCGGTCGCACCTTCCGCAGTTGCATTAGCGGGAACTG
GGCCTGTCGCCGTGCGCTGAGGTATCCACCGTCGTTCAGGTTCGACCAGGGCAACGGCTCGCAAATCATCGCACCGGCGCCCCGGTCCACCACGCTATGCACGTCTTGCTGATCGTATGCAGTGAGGTACTGCGCTACGTCATCATCGAGC
TTGTACGTGGGCACACCAGTCTTGCTCGGGAGCAGGTCGATAAGGCCCGCTTGGTAGCAAGCATCGACTCCGAACTTGCCGACTTGCGCGGCCTCGGAGTCGCTAAGCTCGCTGTCAAGCTCGCCCTTCATAACACGATCGTAGGCCACAG
AGTACAAGCGACGCAGATGCCCGTAGTTCTTCGTAGCGTTCTGCTTCACCTGTGCGTGAATCTTCTCCATGTACATGGGGTTCACTTCTTCTGCTTCCATGATTCGCACTTCCAGTTCAAACAGCCGGCCGATGTGCATCGTCAGCTTCTGAGC
CGTAGCACTGGACTTGCGCATAGCACCCATCTCGCACAACGCGATGCACTCACGAATGGAGATAAGCGCGGCCTTCTCAGCGCCAAGCCGGCGCAGCCACGTCTTGAACTTCCCGCCGGTTCCTCGCGTCTTCGTATCGATCGCCTCTTGCA
GTACGCGCACCACCTCCTGGTGCATCGAAGCCGCTAGCTTCTGTGCCCTCGGTGCGTCTGCATCCCCGTTGCGCGCAGCTTCCATAAGCTCGCGCAAGCGCTCTGCTGCTGCTTCGGCATCGCAAGCAATTTCGTAGGCAAGCTGGGCGTCA
CGGGACATTAATCCTCCTTAGGCGATGTCGATACCGTACGAGCGCACCACGTCGGCGCGCAGTCGGTTGGATTCGGTTGCGTCGTACTCGGCCAGTTCACGGACGATGGTACGGGCCACTCCGTGGTTTCCCGTCTCCATCGCGGCCATCA
CTTGGCGGCGCAGTTGCACCAGCACTTCCTGTTTTTCTGCGTAGGTCATCAGGGCAGCCTCGACGTAACACGACGGTGGATGCGGGCCGATTCACGCTTGCCGTCACTAGCCAAAGCGAACAGCAGGAACAGCAAGTAGAACGCGACGGC
AATGACGCCTGCTGTGTACCGGGCTGCAAGCAGTGCGCCCTTGAGGATTCGTTTCATGTGTTCTCCTTAGTTGACGAGCAGGCCGGCGCGCTCTTGCCGGGTGCTGGATTGGAAGCGGGCGCGGGACCATCCGCCACAGTCGCCGCATTG
GTAGCGACGATACTGGCCGCCCTGGCGGGTATGGCGCATGCCCTTGCTCTTGAGGTTCATCGAACCGCAGCGCGGGCACTTGTGGATCGGCAGGTTGTCCTCGTCGTACTCCGTGGCTTCCAAGGCCGCGACGTTCGGGTGTCCGTCCATC
CACACACGCAACTTCAGGTACAGCTCTTCCAGCGAGACGACATCCTGGCAGTTGTACTTCTTCATTTCCTTCCAGGCTTCCGGGTTGCCCTTCATGCACTGCGACCACAGCTCGAAGCCTGGGAACTTCGAATGCGTCAGCTTCTTCTCGGTG
CAAAGGTTGTCCGTCAGGAACTGAAGGCGGTTGCTGGTGAAGGCGAACTTCTGCTTCGCCACGTCGAGCGTATCGACAACCTCGTAGGGCGACGGCGGCGGCAGACCATTCAGGATGAAGCGTGCGTTCAGCTTCTTGATGTCGAAGCG
CCGGCCGTTGTGTGCGACCACGATGTCTGCTTCATCCAGCAGCGCATGCACAGCGCGCAGTAGTTCTAGGTCGTCCTCGATGTCGTCGGCTTTCGACTGGTCCTTGTAGAAGACCCGGCTCTGGTGCAGCCACTTCGCGGATACCGACAGG
ATGTACCAGTCCATCTGAATCTGGTTCAGCCCGACGTTCTCCTTGAACGTGCGCCACACGTACGCAGCGATTGGCGCTGTCTCGATGTCCAGCGTCAGGATCTTTGCGCGCTTGTGTGCGATGATCTTGGTCATGTCGCTCCTTAAATGTGGT
TGTACTCGGGGAACTTGTTCGCGATGTACTCGCGACGAGCGCCGTTGGCCCCGACACGAGCGAAGACGTTCGTGCCGCCGGGCTGAGGGAATGCGCCCGAGACTCGTGCCCGGAGAACGTTGGCATTAGCATCGTGCTCCAGCCACGCCT
GATTCAGCGTGCAATCGTGCTCCCGCACGATCGTAAGCGGATCGCCATGATGGAACTGGGTCTTGGCTTCAGTGTACAGAAGCACCTGCACCGTGTAGCGCGGCACACTGTGGTACTGAAACTCGTACACCTTCTCCAGCCCGCGATCCTCT
GCGTCACCTTCCGAGGTTTCCGACTGACGAGCAGCATTCACTTGGCCGAGTTCGCCCAGGTCTTTAACCACCGCCCACACGGCAACTTCGCGCAGCTTGCGCTTGAGCGCAACCGGTTCGACGTAGCTCGTAACTACCATGTCCCAATCCTT
GGGAGTACGGCCAAGGTAGACATCGCGGGCTGCCCCGCCACAGATCAGCACCTCTACGCCCTCGTCTTTCAGAAGTGCGATAAGGTCTGTCATGTCTCTAAGTGCTTGCGTCATCATCCCTCCCGTTGGTCACGCAATGCCTTGCGTGCTTT
GATCTCAGCGCGACGTTCCTTCGCAGCGAGATTGCGTTTGTCCATCGCCTTACGGCGCGCTGTTGCTGCGTCAACGTGCGTCGGGTAAATCAGGCCGCATCCTGGCCGCTCGTAGTACGCTACAAGCTGTTTCAGATACTCGACCAGCGCAG
CCGGGTCGAAGGTCTTAGCACCCCATGAGCCGACCACGTTCTTGATCTTGCCTTCTGCGGCGTTGCACGAGCGATGCAACACGCCGCGAATCTCTCCCGTCACGTGGTTGTGGTCTACCACGCCCTCCTTAGGCAGTGATAAATCCACCGGG
CGTCCGCAGATTGCGCACAGTCCGCCCTGCACGATTTGAAGCTGCCTTACTTTCCAGGCTGGCATCATAGCGCGTGAGAGCTTGCGCATTCTCGGCGCGCTTTCGTTGTCGTTCATGTTCCCTCCAGATTGCATCACGGGTTTCCAGCCTCGT
CGTTATCGAATTCGCCCGCAGCCAAGCGTTGACTTGCTGCTGGGTCGAACCAGTCGCGGGTAACGCAGTCATCGAGGAACGCGCGGTTTGCGACAGAAAAGGGTAGCTCATTGAAGTACCTCCACACGTTGTCACCGGGCCAGCGCAGCA
GCCACAGCAGCCACGCCTCGGGCAGCGGATTCTGGTCGATAGCGCGGTACGCGTCGATCACCGTGTTGCACACCGCCTCGATGTCACGCAGCGGGTGCAGCAGTTCATACGCGCCCATGAGTCCGACTGACTTGCCATCGAGCTTGAGCA
AGCCCTTGACGTTATCGGCGGTATCACCCATCACCATCTGCGCCCAAAAGAACTTGAGCGAGCGGCCGAGCAGCTTCTTGTTACCGCCTTCTGTCTCCGCGATCCACAGCTCACCGAACGGATCAGAGGGCAGCACCACACCTTTCCCTATC
TCGTAGTACGGGAACGGCGTCATCCTCAAGTCTTTGTCGTCTGAGCGAATGACGCCTTGCTCGCCGAGCTGATACGCCCGGATCATCATCGCGTCATCCGCCTCGATGATGCTCTCCATTGCGACTGTGAATTCCTGAAGCTCGCCACGATC
AGCGATAGCTTCTCGCAGCGCTTGCAAGAGTGGCGGCTTTGCTCCGCTCTTGCGTTGCCCCTGGTACGGCTTCTGAGCCTTGATGCCGAAACGCCCTGTCTTGTAGCAGCGCTCGTGTGTGAGGTACACCTCACCAGTCGAGCACTCCGCCA
GGAAGATTTGCTTCAGCACCTCTGACTGAAAACGAGAAAGGCCGGTATGCACTGTCTTGACGGTAGCCGCTGCAACGTATGCAGGCCCATCCCCGTCGATCAGTAGCACCCGGCCCGAGTCGCTAACTGCGAAGTCGTCACCAAGGGCGT
CAACATCGACGCCGTTTATTATCATGACAAGAACTCATGCTCCCCGGCGTCTGTAGAATACTTGTCGCTGTCAAGGCTCACGAGGAACCGATGCAGCATTGCGATTGACTGAATCGCCTCTGCGCGAACTTCGGCGTAAGTAACTACTTTGC
CTTCTTCAGTGAGCTGAACAACGGCTTTCGCAAGCTCGCCTACTTCCTCCTGAACGATGTTCAGTGCGTGATGAATGTTGTTCGGCCAACGCGGAAACTTGTTCGTCGCGCGGCGCAGCTCTGAATCTACCCCGCCGACGCCAAAGTGGTTG
CTGGCAGCAACGTCGGTTACGTATCTGCGTGTGTGCATGTCCTATCCTCAAAATGGAATGTCGTCATCCAGGCACGAGCCGCACAAATGAAGCGGCCGTCCTAGCGCGTCCCAGGCGTCTGTTAGACGGTAGGCGGTACTGCCACAGTAG
GAGCAACCTGCGGCACCGCCGGGACGTTTCCCACCACGGCTACCTGCGGAACGATCGGCGCAACCACGGCCGCTTGCGGCACGCTAGAAGGGGATGCAGTCGTCACAGTAGAGGCCTGGATACTCGGCGTAGGCGACGGGGCCGCAGT
CGGGACTACCGCAGCCACGGCAGGTACGCCAGCCACGTTTGGGACTACGGCTTGCGTAGCGGCCGCAGGTGCCGCTGCCACGGCGACCGTGGGGGTAGCTGCCACCTGGGGCATCGCAGCGGCACTGACGGCCGGTACGGCGGCTTGC
GTCTCCTGCGCACCCGCCTTCTGCGGGGTGCCGACCGGAATCGGGCGGTTGTTGGCGATCAGCAGAGCCTCCAGCGGCGAGCCCTTGAAGTCGGTCGCACCGGCGATCTTCTCCTGTTTCCAGTTCTTGGACTTGCCATCGTCGCGGGTGC
CCTCGATGTACATGGCGTCCCACGCTTCCAGCGTCGGCACAGCCCACGAGAACAGGAACAGCGACGGCGCGGGCGGGATGTTGTAAGGCGCACCGGTTGCCATGTCGATCCCGGCCTCGACCTTCTCGATGTACGCGCGCTTCTCGCCCG
GCTTGCCCTTAACGTCGCGATGCTTAATCACGAGGATGTACACCATTCCGCCCAGGAGCTGCGCGAAGTTCTTAGCCTGCCCGAAGTAATTCATGTCCTTGAACAGCTTGAACGCGCGGGCCTTCTCGTTGCGGCTGCGCGCCAGATCGTAC
GTCTCGATCTCGCCGGGGGTGCCATCGTCGTTGACATAGCCGGGGGAGAACATAGAGAACCCGAGCTGGAACATGAGCGCCGGGTCTTTCGGCTTGCCCTGGTACAGTTCGATGTGCTTGCCCTTCTCGACGTATGAGGTGAGGCGGGCA
AGCGTGCGGCCTTCGGGCCACAGCTTGTCGTAGTTGCCACCGCCCGCTTGGGCCTCGTTCATGTCATCATCGCACTCTGCGAGTTGTGCGGCCAATGCTGCTACTTGTTCCGGGGTCATCGTCATGCGTTTCTCCTTACGTGGATTTGCTGTC
GAAAATTGCGAGTGGGCCTTAGCCCTTCTTGAGCAGGGTTTGCAGATACATCAGTGCGCGAGCTGCGGCGTGAACGGCGTGAAGTTTTCCCGACTCATCATCGGTTCCCTTGCCGTCTTTTTGCGTCGCCATTACGTGGCGCAGTAAGGCAT
CACGATGCTGGTCGGGCGTCATCGTCTCAAAGCCCTTAAATGCGTACCCTTTGTGAATCTGTCCGAAGTCGAGCAGATGAGCAACCTCAGCCAGCGCGAGGTCAAACTGAAGGAGCTGAGACATCGGGGGCTTCTGCCTCAGCAACTCACC
ACCGAGTGCCTTCCCTAGGGCCGGGTCTGTATACGGTTCGAAAACGTCAGCGAAGCGCCAGATTCGCGGGCTTGACTGTAGCCGGATTCGTTGTCTTGTGATCGAGCTGTCTACTTCCGAGACTATGTAGCGCGCCTTGCAGGGACCGCCG
TTCTTGAAGCCTACACCATCGTTGCTTTTGAAGCATACAGCATCGCCTACTTTGAAAACCGTCATGCTGCCTCCTTATCGAGAACGCCCGGCTCCCAGTGCTTCTTCGTGCCCATGTTCGGGCCGAACTCAGCAGCAGCAGGGAAAGGTACGT
TGAGGTTGTAGCCGTACTTCTGGCTGAAGTATTGCGGCAAGGATTCCATGATGCCCTTGACGCCAGCGCATACCGTGTCAAGCACGCTGCGATGGCAATCGAGATAGATAGCGTCATGGACCGTGTTGATTACGAACACGCGTCCGCCGA
AGAAGTCGTTAGCGATCAGCCAGCGAATCACCAATCCTGTGATGCCCTGGACGAAGAAACCCGACTCGCCTTGAATCGGATAGTTACGCATCTGCGTGGGCTTGAACTGCATCACCGTCACGCGCTGTCGCTTGCCGCCAACAAACGTCGT
GATGTTCTTCGGGTACTGGCGGAACTCGTAGCACGTGCCGCCCTTCGTCTGGTACACGCCGCGACCGTAGACCGTCCAGTTACCCTCGTCGTCCTGCTCGCGGTGCATGGTCTTGCTGTTCTCGACAGCAGGGAACACCTCGCGCTCGTAGT
ACGCCTCGACTTCCGGGAACAGCTCCTTCTCGTTGGCGATGAACTGCTCCGCCTCTTCGATCGGCATACCCGTACTGAACGCAATACCCATCGCCGTGGCACCGTACTGATACGCGAAGCTCGGCGGTTTGATGTCGGTACGCATCTGCTTG
TACTTAGTGTGCTCGGGGTGTGACTCGTCCTTGCACTTGGCCTTGACCGACTCGTAGCTCTCGCCCAGCTTCTTCGCGAGGCGCATGCAGTGCATGTCGATGTTGTTGACCAGCGCATTGATTAGGTTCTTGTCCTGTGAGAACGCCGCCAAC
GTCACAACTTCTAGCGCGCTGTAGTCGATCTCGACAATGAATCCGTTACGGATGCCGGCCTTGATGTTAGCCAAGCACTCAGCGTAGAACGACTCGTCAATCAGCCCCTTGCCCACTGCCCACAGCAGCCAGCCCTCGCTGTCGTACCGCGA
CTCGAACATTTCCTTGACGCGGGATTGGTAGTCTCCCTCGTTCTCGCCTTCGTCGCCGCGCGGAAGGTTCTGGAAGTTAGGGCGGTTCGAACTGAGCCGAGTAGTCGCCGTGGCCGTCATGTTCAGCATGTGATGCACGATCGACAGCGGG
GTCATGTACTGAAGCATGCCGCTCGTCTTACGCACATTACCATCGTCGTCATACTCGTGGCGAAGGTAGTACGTGCCGATGTCCTTGTCGGCCTTGTTGAAGTTGTTCAGGTCTTTAAGAACCTGCTGCACCTCGGGCGAGAACTCCTTGCGC
TTCACAAGGAATTCGAGCGCGTCTTTCGATGATGCGATCACCGGTGACTCGTCTGCCAGCTTGCGTTTGCCTGTGAACTCGCGCAGGAACTCATCGCGAATCGTCTCGGGCAGCAGCTTGAGGTCGCAGAGCGGCGGGGCGTTGTAATGC
GTGTCTGCCCACACCTGCGCCTGCTCTGCCGTATCGACTCGCGCCACCTTGACAAGACCCTTGTTTTTGCCGGACTTGTACCGCACGAAGTCCGCGCCGAACAGCTTGCATGCGTCGGCTGGCGTGCCTCGCCACACATTGGTTGGGGTCTG
CAATGCTAAGTGTCCGTTCTCGTCCAGAGCGCATACGTGCTCGCACTTGATGCCGCCGATCTCCGTGAGAGTCACTGCATCGGTCTTCACCATAACTGGCTTGCCATCGCTGTCGAAGCGCGGCACTCGATGCCGGTACTTGATCGGACCGC
CGTAGAGCCACGCGCTCATGTGGAAGTCGCTCGTCTCTTTGAACTCGACTTCCGCCGGGTAGTCAGTCCGCCACTTGGCGAACGACGTGCGCAGGTTCGCGATAAGTTCCTCGCCCTCCTGAAGATGCCGCTGCGCTGTGTCCCGATTGATG
AGTAGTCCTGCATCCATCGCGTAGCAGTTGAACAGCATGGCTTCCATCCGCTCCAGCGCCATGTCCCACATGCCGCGCTCGGTGAGCTGCTGGTACTGCCCGTAGAAAATCTTGCGGGTGTTTGCGATGTCGCCCCGCTCGGGCGAGATCA
GGTACTCCAGCAGAAGATCAGGGTCGATCTGCGAAGTCAGCACACCCTTCTCCCACAGCGCCTTGATGCCGTCCACCTTGTGTTCGCCGCCGTACAGCGGCGCAATCTCGTCCAGCGGCGGGTACGTGTCTCGCTGGTTGGAGAGCAGGTA
GTGTGCGATAGCTGTACAGAACACCCGCCCGCCGCGCTTGAGGAACTTTTGAAGTTCCGCACGCTGCTGCGCAAGCATCCAGTCCAGTTCGAATGGCGCATTGTGGCAGACGAGCAACCACACATCATCAGGGATGGTGACCCATGGACG
CGAGTGGGCTTGCTCTTTCGAGTCGTTGCGCAGGTACTCGATCGCCCCGCTGTAAGGCGTCTCTTCGGTAGCCCAGCCGTTTAGCACGACGTAGTTGTCGGGGTGGCGCGGTGAGGCGGTAGCGCCACAATACGCGTGGTTCTCCGTCTCA
AGGTCCATGAACATTATTCGAGGCATCCTGACTCCCTTAGTCTGCCTAACGGATTGTTGAGCACGTATGTTGTGCCGTCGTCGCACTCGACATGCAGGCCGCAACGCAACGCAAGGTCGCGATGGGCCGGCACGATCTCGGCAGTGCGGAT
GAAGTTGCCATTGTTGAGCGTGCCTAGCAAGGTGTTTTCAAGCGCCATCCAGCCCGACAACACCTCTACCTTGCGCTGGCCTCCGCCGATAGGTTCCCAGCTCAATCGGCCACCTTGATCCAGATGAACGAGTTGTCCAGGTTCAGCCGCTC
ATCCAAAGTACGTCCTCCGTGGCACCGGCGTTTGCCCTTAGCTTGTCGATGGTCGTTTAGCTCGCCGCAGTATGACCCCGAGTAGTATTCGAAAGCGCAGCCATGGCATCGGCCGCTGGCATCCTTCTGCTTCTTGTACTTATGACCGTCGTA
TCTCATGCCTTATCCTCCCGGAAACGTTTGAAGCGGGGATGCCGATAGCCACCTTGACGATCGCGCATCATGTAGATGAACTCGACCCAGCGGCCGATGAACGCGGCTGGGTTAGCCAGCATTTCCCGGCCAAGCGCATGCTCGATACCGG
CGACGTTGGCTGTGCTCCCGTCTTCCAGGAGTACAGAGACGCTACCAGCTCGATCCAGCGCGACCCCTTCGAGGCTGTACCCTTGATTGATCCCAGTGATGACGCCATCTGCATCTTCCTCCGGTTTGTACTTCAGCCAGCCGTATGAGCGCT
TGCCGGGCTCGTACACGTGGTCCCGCGTCTTAACCATCAAACCCTCGAATCCTCGTGCAAGCGCGTCTTCGAACGCGTTCTCTACATCCTGCTCGCTGTCCACAAGGGACCATTCGGGAAGGCGCAGCGGTACGCCTAGGCCCTCGGCAACT
TGCGCAACTTTTGCACGTAGTACGCAGCGCCCAACCGTGCCCCCGTATGGCAGGGGTGCGGAGTCAGGCAGGTCGAACAGGATGAACTCGACCTTAGCGTCGCGCAGGTCTTGGGGTACGCCCTTTGACGAGCGTACCCATCGATACGTG
TCGTTGAAATTGCCGTTCACGATTACACCGCAATCTAGGCGAGTCGCATTGATGCGACCCATAAGCTCGTTAAACGGCTTATCAAAGTGGCGCAGGTTGTGCAGCACTTTGTCCGCGTAACTGCGGAAGATGACGCGTGCTCCCTGCTCATA
GTCGGCGTACACCGCGCGCTGTTCATCGGCCGGGGTACGTCGAATGTCGCAGCGAATCTCGTCAACCTTGATCTCCGCAACGGCGGGCCACTTGATCTTGTGCTTGCCCTTGGCCCACGTGTGGCCCTTCATCAGCGCTTGAGCCATGGTGC
CTCCGCCTTAATCCCACGAAGCGGGGCGCGCAACTCAATACCTACACCGATCCATTCCGCGTGCATCTCGATACCGAGTTGACCCAGAATCTTGCGCGTTCTGCATAACAGTTCCCGCTGTTGCCACGCCGCCACTGCATCTGGATCACCGAA
ACTGCAGGTTTCACCAGGATTCAACAGTGCTGTGCCGATGGCGGACAGGATGATCGCAGTGGTGCGACCGGACCCACGCACCGTTTCCAGGTGCTGGTTTCCCATAAAGAGTAGTTGCGTTGTCTTCATCAGTCCTCCGAACGGTTTAGGC
GGTAGTGGATCACGTCTTTGCCGGTAGTCTCGCACCGTGCCGCGAAACCCTCGGCCACGACGCCGCGCTTGACGAGCTTGGACAGCGCGCCACACAGCGTGGCGATCTCGATGCCGGTTGCCGTGCTGATCTCGCGCCGGGTCATGTACA
CCTTGCTACCAGCCAGTGCCGATACGATTGCTTGCGGCACTGTTAGGTACTTAGTTTGCGAGTAGGCTTTGCCCTTCGTCTCCTTGCTGAGTAAGCTCATGCCTTAACCTCCTTCAGCCAAATGTGCGAGCCGCCGTGCATTTCGTTCAGCGTC
TTGCAGATGGGTTTGCTTTGCACCTCGCCATCGAGAAACGGCCGGGGGCATCCAGCGTCGCCGCCGTCTACCCACACGTCTAGAAACGTGCAGCCGAGGCAGGCTAACTTCTCGTCCTGCTGCTGAATCCAGTAGTCCATCACGCCTCCGG
GACGGTCCATGTGTTGAGTTGCGGGTCGAACACAGTCTGAAACTGGTTCTCGCTCTTGCGACCAGCACGAGCCAGTTTGTTCTTGGGCGTACTGATGCCGCGCACATTCGGCGCGCTCGATAACGCCCCGCCCATGAGCACGAGATCAAGT
GTGGTCTGGATGCCGACCTTGCTGTTCTGCATCGCAGAGATTGGAGGGAACAGCATTTCGAATCCCTCGCTCGACACTTGTACCGTGCCGCAGTGTAGCATGTCGTGAATGGCGGCAAGCTCACGCATGCCGTTCCATACTTCCTCCAGTTG
GCCGATGTCGTTCGCCCCGCCGCCGCGATTGCTCACGGCGCGGATGCGCCCGGTCATGTCCGTGACGCAGATTGCAGGGTTGTGATGCTGGATGATCTGCTCCACCTGCGATACGTTCTTGCCATGGATGTTCTTAAGGCGGATTGCGCCG
CGCCCACCGATCGCGTCGGCGTAAGCCTGCTCCAGCAATCCCTCATTGCTCATGCGGTACATCGCCTCGCGGTCGATGTTCAGCACCGTCTGGTACATGCGAGGCGTGATGCGCTCGGCCTGCCCCTCGTTAATCAGGATCAGGATCGGGC
GCTGCGTCGCCTCGTACTCAGCGCGTCGCTGCTTCGCGATGTTGCCGAAGATGCGACAGATCAACGAGGTCTTGCCCTTGTCGGTCGGCATCGCAATGGCGATGTTGTTTCCAGGGCGCAGCCCCTTGATTGCACTGGTGAGCGCCGGCCC
GAAAGCGTCGATGACCCAGCCGCCCTCGTCCGCATCGTCTGCGAGGTATTGGGAGATCGGACCATCGGCCCACGAGGAAACGCCGCCCTGCTGAATCTCGCGGCTCGTCTCCAGCGCGAGAGCCCGTAACTCGTATGCGAGATCGACTTC
CTCGCCTGAGTTGTATCGAGCCAGTAGTGCGCCAGCACGGCCGGACAGGTCGCGCTCACGCAGCGTGTTCTGCACACCGACGATAGCATCTAGCGGCGGTTCTTGGTGGAGCTGATCGGCGAAGTGTTGCGCGATGGCGATAGCCTCGGC
CCCGCCGCTCGGATCGGCACGTAGCGCGATCAGCGCCTTGAGTTGGTCAACCTCGACGCGCTCGGCCTCTGCATACGTGTTGAAGTAGAGCTGGAACCACGCGAGCATGGCTGTAGTATCGCCGGAAAGCATGTCGTCGGGGACCGCCG
GCCGCAGTTGAGCATACCGCCGTCGATCCCGCAACGCGTGAAGGATCAGGGCATCACTCATACTGAATCTCGACAGTGGAGGTCTTGGTGAGGCGCCTTACAAAGTCATCCGGCCACCTCAGCTCGTACTCACCATCCGGGAGGTGCGGA
AGTTCCAGGAGTGCTTCAGCTCCAGCCCGTGACTTGACAAGGAACACGATACTTGATTCAACGTGCTTCAGTTCCAGCGAATCGAAGGTAGGCATAATTATCTCCAGTTAAATTGCGAGTAGGCGCTGCACGTGTTCACGTAGCGCGGCTT
GCGTCATGTCCTTCGGGTCCAGCCCTTCAGGTGCGCACGCTATCGCGCCGCTTGACTTGATTCCTAGAGCCCTTAGCCGACGCGCGTTTGCTTCCGCGCCTTTCCGCCCAGGCGCATCGCCGTCGTAGAACGACTCCACTTGCTGGGCTTTGC
ACTTCAGCAGCGCTAAACAAACGCTTGAGTGTGCGCTCGTCCCAAGTGTACAAATCACACTCGACGTAGGCAATGCGTGCTGTATCTTCAGCAAAGAAAACGCGTCTTCCACTAGTAGCCATTTCGAGGATTCGCTGCTCAAGTTCGCGGAA
GTCACGAAATGCTGCCGATCGTATGTTATCCACTTCATTGGGCTTGACCCTGAAGTGTCGCGGCCCATCAAGCCCTGGGGAAACGCTAATAACAGGCGTCCACGCTCCCGACTCCATGAACTGCCGTGCGGCATCATACATAGGTCCAGCCC
CTTTGCCGCCACGAATGAGGCCAACTGCGCCTGCACGTAGCTCGGCAAACTTCCAAGTTCCTTTCGGTCCGTCGGGTGCGTCAACGACGATGATGCGGCCGGAAGGGCTGAGGTTACAAGCACGTGATCCTTCATCACTACGGCACCACTC
TTGCAGCTTTGGCAGTAGCTCCACCATCTATCTCCCGCGTTACCCACCACTAAATTCTCGCGCGCCTCGCGCAAGTGCCGATGCCGACGTTGCTGTCCTATCGGCACGCGCTTGGCAAGGTGCAACCATTCGTCGTCAGGCAGACGTGCCAT
GTTGCCTCCAGTAAAGGGCTATGCCTTGGTGGCAGTGTGCGACCTCCGCGACTCGCTCGCGGCGCTCTCTACTGTTCGCAGGCAAAGGTACTCAGGCGGGCTCCGTCTCCGGAGTTGCACGCAACGTTCGGAGCACGTCCCTTTACTATGC
CAGCTACTTAGCGCTACGCGGGACTTATCGTCATAATTCCCCATTCGCTATCTGAGCTACACCAAGGCACAGCCCTTTAGGCTGTGCTACTACTTACAGCTCCAGGCGGTTGTTGATGTCCTGCACGAGGGCTGTAAGCTCTGCAACCGCTTC
CGTCGCGTGCTGCAAACGCGTCCTCAGGTTCGTGCTTGCTGGACGCGTCTGTTCCGTTTGGCTTCCTACCGACTTCATCGGCGATGTGACCACTGCGAGCGCGTTGCTCAGGGCAACGAGTTCCTTCTTCAGCCGGGCCATCTCATTGCTCAT
TGCGCCTAACTGAGCGACGATACCCAGCGTAGGCTCGGCTGGGGACATCGCCCGGTAGAAGTCCGACTTCGCCATGTAATAGTCCTCTAGCGTGTAGTTCGACATAATCACCTCATGATGGTAGTGATGGCCCGCTGCATCAAGCACACGC
AGCGACCCAGGTAGTAGACGCCGCCGGGCACCGGCCCACGGCGAATGCTAAGGCTTCGAACCAGGCTATGGCTTTAGACCTGTTGGATGTCCACGATCTGGCTGTCCTGGATCACGACGGTTTCGGCATCGAAACCCTGGCCGAAGTAAA
TCTTCAGCCGGCGGTCGCCGTTCTCCAGGGTCTGCACGCCGATCACGGTCGCAGCGACTTCGCGGGCAGTCTCGGCACGGCCCACGCGGGCCACGATCACACTGCCTTCCGTAACCTTATCGAGCAGGTCGGCTGAACGGAACTGCGTCTC
CAGCTTCGCGATCTCGGCGGCGAGCTTTTCTTGCTGCGCCTTCTTCGCGGCGATCTTAGCGGCCAACTTCTGGCTCGGCGTCAGTTCGACTGCGGGCTCACCAGTAGCGACGGCACCAGCCGTCACGTTGGCTGCATCGGCCGCAGAGCCA
GCAGCGTTTCCCAGGACTTGCGCCGTCAGGTCGGGCTCGGGCAGGGCCGGGATGTTCGTGCCTTCGATTACCCCTGCGGCTTGCGTAGCGGCCGGCTGTTCGGTCGGCGCAGCGACTGCGGGGGTAGGCACTACCTGGGCGCCCACTGT
GCAAGGGGTACGCCGAACAGCGTCAGCGTAAGCGTGCCGGTAGCGGGAATGGCCTTGAGCGCCTCCCCTACCAATTGTTCTTTGATGCTCATTTCCTAGCCCTCCGACGAGCGGCCAACGAGCGAGCACCGCCACCACGCTTCTCGCGTGC
GGCATCCTCGTACCCCATTGGATTGTTCATAAACTCTCGCGCCTCTGCTGCTGCGCGCTTCTCTGCTGCCTTTTCTTCATCCTCGACCAAGCGAGTCTTGTGGAAGCGTATAGCACCCGCCACGGCTTCCAAGCGGTCATCATGGGCCAATGA
ACCACGATCAGTAGTGATGTTGCTCATCTGCGACCACATGCTGTACTGACTGCGCTTCTCAAGGCTGTGCTGGGCGTTGTACTTCTCGTCATCAGCGAACACCTGTTGATGCACGATCACACGGTGACGCTGCATAGCACTCACGAGCGAGT
CGATGATGCGGCGCTCCTTCTGGCCTGTGCTGTACTCACCCTCAACGATCACCGTCTTGAAGAACGGCTCAGGCGCACCATTCCAATCCTTTGCGGCCTTTTCAAGCTCACCACGTAGGTTGATCTCAAACAGGCCGTGGCCCATGTTAGACT
CACAGCGCACGTACTTGATCTTGTACTCCAGCAGTGTGCTCAGGATCACGCGCACATTCTCGGTACGGAAGCCGCCCCTCAACCCGCCCATCGTGAGCAGGTGGATGTACGGGCCTAGCGCACCGGAACAGGCGAATGCAAGCTCATCCTC
CCCGCCGCCCGCTGGATCGCAGTACATCATCAGGTCGGTCAGCTCGCGGTATGCGGTTTGGGCGCTAGCTGCGTAGTACATGCGCGTCTGCGCCACCGGGAAGGTAGCGGCTAATGGCACAAGTAATGCGGGCTCGGCGCGGTACGGGA
TGACTTCAGGTACAGTCTCCCAGCCGAAGTTAGCGACAACGAGGTCACTCAGGCGAAGCTGTTGCCGCGCCTCGTCAGCGAGCGAGGTATCTAGCATGTACTGCAACTGGAAGCCCTCGGGTCCCTGGTCTAGCTCCTTCTCACACAGTGC
CGATTCGCCATAGCGTTCCGGGTCTGTAGGCTTGCCACGTGTGCCATCAAGACCGCCGCCGGACTGCAATGTAGGATCAGCACGCAGGCGGGCAAGGATGCTCGGAGCGAGGCGCGTACCATACTTCTCCAGCTCGCTAGCAGTTGGGTA
TCGTCCCGGCCAGATGCGCACTTCAAAGCCACGGCCCGGAAGCGTGTTGTAGATCGAATCCTTCGTCTGAGGCGTGCCCAGGTACAGAATGTGCCCATCCGCGCAGATCGACGTGAATTCCTTCGACAGCAGCAGAAGGTGCGCTCGCTG
CGCAGCGGTCAAGCCATTCTTCGTCGTCTCGATGTCATCCGGGATCAAGAGATCAGCCCGCTTGCCTTGGAGCTGGGCGGTGATGCCCACACAGGCTACGGACGGCGATTTGTCAACCGTTCCCCGCAATGCCCAATGGACGTCAAAGCCA
TCCGTGATAGAAGTGCGGTCACCTGCGCTGCGATCAGGTCGTAGGTACTCGAAAATTTCCCAGGTCGTGATAAGTCGCACGATCAGGGTTGCTACTTCGGATGCTTGAGTCTCACCACCAGACACGATAAGAACCCGCGTGGTTGGTTTCT
GCATCAAGCACCACACTGCGTATAGAGCAGCGAGGGTAGACTTTGCTTCCCCTCGTTGCGCCATCACCATGCGTAGACGGGGACCGGTGGCCATAAACTCGGCGATGTCTTCCTGAACGTCAGTAAGACTGAAACCAAGATACACCATCCC
GTCAGCGGCAAAGGTTGCAAAGTCCTTGTAGTGCTCCGCCATAATGATGGCAATCTTGAATCGCTCTGCGATGTCCATCGGTCCTCCTTGTTAAGTTGCCCCTGTGGTTAGCGTCTGCTCAACCACACGAGCTAGCGCGCTCTCTTTGCGCTG
TTGTCGTGCTTGCGTCTGCTCAGTGAACTTGCGCCGCAACTCTGCCGTGGTATCTTGGTCGGCAGGATCGCAGGTGATGTTGTTGTCCGACAGAAACCCACGGATCACCGACATAGTCGCGGCATCCGTAGGCATGTCGTCTTTCAAGTCGC
GATTAAGCGTCTTGGTCATCTGCTCTGCTAGTTTGCGATGCAGTTCGTTGAGCGACGCGGTTGATGCCGCGTTGCTCATTGTTCCTCCTTAATCCTCGAAGCCGAGGTAACCTCGGTAGATACTGGAAGCTGCGTCTCCGCTCGTCACAATCT
CGATAGTAACTTCGTCACCAGGATTCAGGACCAAGTTCACATCGACGTTCACAGAGAATGCGCTATCGCCTATGTAGACCTGTAGCCCTGTATAAGCGTTATTGTAGTAGAGGCGCAGTCGTGCCGACTGCCCAACCCCCGGTGCAACACTT
GCGCCGACGTACAAATGCATAAGGCGTTCTTGGCGCGATGCCACATACGGCAGACTCATAGTTGAGCCCCACAGGCCACCGCTAGTTAAGAAACCAGTCGTGCCTCCAGCTACAGGGCCACCTGAGCCGATAGGGTGTGTCCGCCGAGTC
GTAGTGTTAGTGCCTAGCGTCAGTCTCGGAAGATTCTGTGCCATAACATAATCCACCGATGAAGAGCCGTTGGCGATGGGCGGCTTGCCTGTTCCTGGAACCCGGAAGTCGTTGAGTC
CAACAATGAAGCCAGAGCTGGCCCCCGCATCGATCACCAGCCCCTCAGCCTGTTCTACATTAAACACGCCCTGAGAGAAGTTACCGATACGGTTACCGATCAACATCCAGTTAGAAACGCCCGAGAGCACATGCACACCAGGGTAGACGTT
ACTGAAGCCAATGCGACGGCTATTGCGGGAGATCGAAGCGTTGTAAATACGCACGTTGTTACCGCCTCCGAGCTGCACGCCTCCACAGTCATTGTCTCGAATCTCACCGCCGTTCCAGCGGATGTCGTCCAGGTTCGGACCGATGAAGGCA
ACACCCACGCCACGCTCTGAGCCGGGAGGGCGTGCTGCGCCGCCCCCGGAACCCGCAGACCAGCAGTTGGTGCACTCAATGTCCAGCACAGGAGCCTGCGAGCCGTCGAACGTCCAGCCCTCATAGTATGAGGTATCCGCCAGCACTTGG
TTGAACTTCAGGAAGCGCACCCAGGAACCCGCCGGCGGTGCGCACACGATACCACGACCGCATTGTGTAACGTCCACTGTGTTCAGGAACTCGCCAGAGCCCTGCGAGAACAGGATACCAGTGCTGTTGTATGGGTCAGAACCTGTGTAA
CCGAATCCGCTGATCTTCAGGTACTCGATCATTGTGCCCGCAGTCTCCGTCCCTGCTCCGCTGTACTGGGAGAGGCGGATGCCGTTAGCGTGGCAGAACAGAAGTCGGCCGTGGCGAATCTTCACGTAGTAAGAGCCGTTGACCACGATGC
CCTCCGCAAACGACTGTATATCGAAATTCTTGATCTCGAAATTGTCGTTAGCGTTGGTGATCTCGACCGCCTGCCCCGAAGAGCCCTGCGCGCCAAACGCCACGTTGCTCCGGATTGTCATGCCCTCTATACCACCGCCCTGCTTGTACCCGA
GTTCCCACTTGAATAGACCTTTCGATAAGTCGTCCTGCACACACTCGGTAAGCTGTGCGCCTTGGCCTTGCAAGTACGTAACGTCGGTGAACGTGTGTACGTCGTTGAAGTGGTACGTGCCCGCCTCGTCAAAGTACAGCCGGGCCTTGGGC
TTAGCGGCAATCAGCTTGTTAAGCTGTTGGGAATTGTACGCCCCTGTGGCGCTGGGGCGGATACCCCAGCGGGATACGCTGATGCGGCCCTTGAACCAGTCTGCGAGCGTAATGCCGACCTCTCCTGCTATGCCTCCGAAGAAGCCGACAA
GCGCCGCTCCCAGTGAGGGGTTCGTGGTGCTTGCAAGGTCATCGCGCACCGTATCCACACTGTACTGCTTAAGCGTGGCTAGCGACACAGAATCCCCGTCATTGGTGGCAGTGCCCAGGTTCTTTAGTACGCTGCCATGCATGTCCAGGTC
GTGAAATACGTCGGTGATTCCTGCGCCCTCGGCGTACTCCTGCGCGAGATAAACCATCTGGCGGAAGTTCGTATCCACTGACTCGTTGGTAAAGCTCGCTCCGAGAGAGTACACATTGATAGCCCGGTCGATGCGCGAGGCGCGGTGTACT
CGTACTGTCACGCCGTCGGCCACGTTAGGTGAGAAGCTGATCCGCTTATCCGTTGTGCCTACCCAGCTCCATGTGCTGTCGAGCGTTTGCTCAACCTCGTCAAAGTAGACGGAAATGTCCGCCCGCTTCTCGTACGCAATGGAAATGTCCAG
GTAAGCCAGCGTGCCGTCGGAGACGGCGAGCTGGTTACTGTATGCCATTAACCCTCCTATTCTTTGTTGTGGCCGGAGCCTTGGAACGAAGCTGCAAACGCCTTAAGCCCCGGCAGAATAGCCAGGATCGGCACAGCGCTAAGTGCGCTG
CTAGCTGCGCCACTGAAGTTACCGCTAGCCGCTTGGCTACCAGTCTTGTACAGACGGTCGATAGCCATCAAGCCACTAGCGCCAAACTGTTGCTTATCACCCGACACAATGCCCCACAGTTCTGAGAGCAAGCCCATAGAGCCCATCTGCCC
AACTGCGAGCCCAGCCAGTTTGCCTACATCCGATTCAGGTTTACCGCGTAGTACGCTATTCGCATAGCTTGCAGCAACAGTAAGCGGGAACTGGTACAGCATCAGCAAACCAAGCCCAGCAAATCCGTTACGGTGCAGCGTACCGGCTAGC
ACTTTGTTGTGCGCGCCGAGCACGAATGAGCGGAACGTGAAGATGAACTTGCCGACAGACGAGAACTGCGCAAAGGCGGGAATCTCACCGGTGCGATTACGCAGCACAGACTCGTCCATCATCTTGGCTAGCGGACTGCGAAGCTGTTCC
CACGTACCATCCGCCCAGCGCTCGGTATTCGCCCCATGCGCTAGCAGGTCTGCCCGTACGTTGTCCAGTGTGCGGCCCTCTAAGCCGTAGCGGCTCAGGACTTCCGTGTAACGCCCAGGCTTAGTTTCCCTGGCAGCTTGCAACAGAGTATC
GACAACCAAGTTAGCTGTTACGTTTGCTTGGTTGTGGTGGATGAATCGCATTGCGTTCAGATACGGAACGAGCTGCTTACTTTGTTGCATAGCTAGCATTACGTGATCGCTAACCGGCAGTTCAAAGTTGTCCTCCATCTTTTGGACGTAAG
GACGAATGCGAATGTCTTGGTACGAGTTGCGCGCCAAGATACTTTGCAGGCTCTCCGCATTTGCGTGCGACGTGTCACCTAGGAGCTGGCGGAACACCGGCATCGTCTTCAGTATTTCCCGAGGATGTCTCAGCGGCTCCTAGGGCTTCCT
ATGGCTTCTGAGGGATTCACATGCCTTTCCAGCGCAAAGGGACAGGAGTGTCTAGGGGAAACCCTAGGATTCATAGGATACCGTGTGGTTTCATAGGGTACTGTAGCGGCTCGCTCCCGCTCGCCCGCTATCTGTCTCTTTTCGTACAGGTA
TCTATGAGGGTATTGCTAGGGATACTCTAGTGATCTCTACATGTATCACTAGGTACTGTGTAGGTATCTCTAGGATCTACTGTAGTGTCTCTGGTGTATCTCTGGTGTATCTCTGGTGTACTGCTAGGTATCATGTCTTGTATCCGTGCATCGC
CTCGTTCCTCGGCTCGCCGGCTACGCTTTGTTTGCGCTTTCCATCGTGTGGCACTCTAAACGCTATGGTGTTAGACTATAGCTCTCATGGTACTAAGGAGATAGCATTGACTAGGGTAAGGGGTAAGGCATCTAACGACTACAGGAATGACT
TAGTGCTGTTCAAAGCTACTCAGTACGCTAAGCTTAAGGAGTTACTAGCTAGTGGTGTAGATGCTAGTACAGCTAGTGTCCAAGCTACTGAGTACGCTAAGGCTAGGGTAAGTGATAGGGCTAAGGCTAGACGAGAACGTGCTGCTAGGA
AGAAAGTGCTTGACAAGGCTTAGGAACTAGCGCATAGTTCGATCCAAGCACTAAGCAACAAGGTGCGAGACGCTAGGTAACAAGGCGAAGAAGGCCAGCGCTCTAACGAGCAAGGCTAAGTAGCTGACAGGGCGTTACCGTTAGCTGAT
AGGATTACCCTGCAACTCAGCTAGTGTCTAGTAGTTGACAGCAGTAACGCAGTATGCTGTAATGCAGTCACGGTGTAGCGCAGTAGTGATCGAGAACGTTAGCGGCCTAGGTTGCTTCCTGGTAAGACACAAAGCGCTTGACACTAGCAG
CACAGCAGAGTAGGATGCAGTCATGCAGTACAGTGTTCGCAGTACCGGTGATTCAGGCCGGACGTAAAGCGAGGCGCTGAGTAGTGATCCCGGATAGCAACGGGGCGGGTAGCGAAGCGATACGCGGCAAGTAGGCAGTAGGGCTTA
GCGGGTAGCAGAGTGATACGCAAAATTGCAGGTGTTAGGCAGTGACTACCGCGAGGCGCAACCCTGCTAGCGGATACGAGCCGAGACACACTAAGGCGCTAGGCGCACGAATGGGCGGCACCGCTTAGGCGGGAATGGATGCGCCGG
GAAACAGGCATCCTACATGCGTAGAGCTTCGGCCGATGGCTGAGACTGCGCTGTTAGCTACGATCGGGTAGCGATGACAACGGCTTGCCGGGTGATTCGCGATACGATGACAGGGCGACAGTGACGGGCAGTAAGGCGATGGGTAGTG
AATGGTGCCCTGTTAAAGCGAGCAAGCTACGAAACCTCACCTCGAAAGAGGTGTTGTAATTTGGTCGGCTCGACCGCTAGGAATCAAGTCGGGCCAGTCTAGTACCTGAGTGCAACGCAATGCGAAACTGCCCTAGTCGTTGGACTACTG
GCCGGGACGCAGAGAAGCGGGCAGGGAAAGCAACGGCAGGCAAGGATGACGCGCCGGGCCGACCAAATTACAACGTAGTACCAACCCTGACCTGAACAGGAGAATCATCATGGCAACCAAGGAAGTTAAGGAAAAGACCGCGCCGAA
GCAAAAGGCGTTCTCGCTTATCACCAGCCAAGCCGAGCTTAACGCGGCCATCAAGTCGATCGGCACTCGCTCCGCACGGCTTGACGCGGACATCCACCGCGCCGCCGTGAGCGTGATCGTACACAGCGCCAAGCACAACGATCCGGACGT
GGCAAAGCGGCTGCTGGACGCGATGGGCAAGACGATGCGCAAGTCGGCCATGACCGCATGGCTGTGCGCATACGGTGCGTTCGCAACCGACGAGCATGGCGCACTGGTGTACGTGAAGGAGAAGCGTGAGTCGGTGCAGACTGAGGC
CAACGTTCACGCCGCGATTGCCGAGCCGTTTTGGATGTTCGCGCCGGAACCGAAGTACGTGCAGTTCGATCTCCAGAAGTCGGTGGCGGCACTCCTGCGCCGCGCTGAGAATGCCCTGGCGAACGAAGCACAGGACGCTACGCTTATTAA
GCCCGATGTCCTCGCCGAGCTGCGCAAACTGGTCCCGGCGGACGCCAAGTAACCGAGCGTCGATCATGTACATCCTGTACGTATGGCTGATCGGCTCGTTAATGATTGGCGAGCCAGTGACGCCTGAGCAGTGCGAGGCGCAAGCCATCG
CGGCCCGGCAACAGCACGGAGTGCGTAATGTCGAGTGCGTTCGAGTCCGGGAAATTTGAGGTGAAATGATGGAACAATTCATTGTGGTAGTTACCCAGCACCACGAGGGGCGTTATGGTGGCGTGCTGCACGACGAATCGGATGAGCCG
TGCACAGGCACCCGCGCAGAAATGGAAGCGCTCCGCGATGACTTCATGCGCCGCTTTCCGGGCAGCGTCTGCGAGGTGCGGGAGGATCGATACGAAACCCTGGCGGGAGAAGCGCCACGCCGCTAAACAGTGGGACAACCGAGATTGG
ATGGACCTATGATACCGCACTACGAAGAAGCGTTAGAGCTTCTGCGCAAAGACCAGCATCAACTCGCGACGGCGATCTCAGGAACAGACTACCCGAAGATGCGCTTCCGAGATGTCGTCAAGCCCGACTGGTATCGCATAGCGCGTGCGC
TGTGGGCGTACCACAATTTGGTTGTCGCTGATCGCGACCGTTTGCGCAAGCAGGTAAGGGGAACCTACGCCGGCCCAGGCACCGATGGCCGCTATGGCCGATAAGGAGATAATGGTGGACCAACAGAACGTGAAGTTCCTGCGTGACCT
TCTGAACGAAGCGGGCGTAGACAACCCGCTGGAGCTGGAAGTCGAGATTGTGCGCGCCGACGGCACACGCGTTGTTGATTTTCAGCAGGTTTCGCTCTATGTACTGTGGAGCAAATCGCCGGGAGCAGTGCGCATCCGTGTAACTGCGAA
CGAGGTGTAGTGTGGTCATTGCAATCTTACTCGTGCTGTACGCAATCGCTGACGTGCTGTGTCGCGTGAGCGATAGGCGCAACACGCGCTGGAGTGTCCAGGTTATTTGGGACGGCGATTCGTACCGCCATGCCGCGAAGTCTTACGACG
ATGCGTTAGCGTGGTTGGCCTGCTACCGTTTCGGCGAGGCATTCATCGATCGCACGTTTCACGGCACTACTGAGTGCGTGGCGCGGCGCATCGCCTACTGACAATTTCAAACGCGCAAACTACAGGAAAGACCATGCGTGCCTACAATTCG
TACAGCCAAGTTGCATTCGACGCGAAAAAGTTCAACATGTGCGTAGCGCATTTCCGCGAGGTGATGCCCACACTGCGTGAGCAGTTCAATTTCGACACGATCGTCATCACCGGCAAGTCCGGCGCGTCGCTGGGGTTTGCAGTTGCAGCAG
CGTGCGGCCTTCATGTCGTGTACGTTCGAAAGGGCGAGTCGTCGCACGGCGACTACATTGAGGGTGACGGCCACGAGTTTGAGAACTACGCGTTCTTCGATGACTTCGTGAGCAGTGGCGAAACTCGCAAGCGCGTGATTTATGAGCTTG
AGGCTGGGCCTTAGAAAGATGCGAATACGCTAATGCGCCTAAGTGCGTTCTCACCATTGAGTACGACGGGGAGCCGGACACTGCTAGGCTTATCTGCCGCAAGACGCCAGGGGTTGACGGCCCGAGATACACCGGCGGTATGTACTGGT
AGGAGGATACATGCAAAGCAACAACACGATCGAACGCGTTCGAAAGCAACGCCTGGAGCAGACGGAAGGGCAAGCGCTGCGTGCTTGAGCGCCGAAGTCTTACCTGCTTCGTCAGTTACGTTTGTGAGCACGTCCATCGCATCCTGAATA
CGCTTCTGCGAAATGCCAGTCGTCTCCAGAATGGACCGCACTTGTTCTGCTGCCCCGTTACCGACGTGTCCGCGAAATGCTTGATCCTCGAAGTAGCCCTTAGCCCGAGCGCGGTGCAGAATTGCATGCGCGACATCCTCGGCCAAGTCGCG
CGTCCATTGCGGATTTGCGCGCATGATACCATCGGCTACGACATCACGAACCGCACGCGACGCCTCTTTCTGAGTCAGTCCCTCTGCAACGAACTTAGCCTCAGCAGCTTCGATGTTGGTGACGCTCCATTTCCGAGAGAAGTACGAAACGT
TCTCGTCCACTGCGTCAGCACCCAGCACACCCGCCGCCTTCATTTCGCGAAGTGCAGGTTGCGTAGCGGCGGCGTGTGCGTCAGCAAGTTCGGAGATTGCCTTCGGCACAGACGGGTCAGTGATGTTGGAGTTACCTCGACGGATCACGTT
GTCCCGACGTGCCAGTTCCTCAAGAACTTCACGTTCGATCGTACGTTGAGCCGTAGCAGCTTGTCGCGGTTGCAGCACGCGCTGCAACAGCCCGGCATTGCGCCGAGCCATTTCTGCCTTGAGCAAATCCTCGTAGGCATACTGCTTTGCTG
CGAGGTCTGAACGAATAGCTTGGCGTTGAGCCGCAGCAGAGTTACCCGAAAGATTAGTCGGGCTCTCCACAAGCAGATTAGCGACCCTCGCGCCCTCCGTACCCTTAGCACTCATGGTCTTATGGAGTGACAACTCAAACTTGGAACCCGC
AGCTTTGCTAGCACGCTCCAGCTTACCGGATACTGCGGCTGCGAGCTGTTGCTGCGAACCTGTAGGTGACAGTTCCAGCACATCACCGGTAACACGGTCGGCGACGTTAAGACGAGTATTAATCAACTCGTCCGTTAGGGACAGCGCCTTG
GTCAATGCGCTCTCTTGATTGGGCGCAATGCCCAGGAGCTTACGAACCAACTCTACCATCTTAGACAGCGCATTGGTTGCACCTGCAACAGGAATCTGCGAAAGGGTCCGCGTGAACTCCGTATCGCCGGAGTACAGCCCGGCCACAAACT
CACGCACGTTACTGCCGAAATACTTTGCCTGCCGCCCAGCAGCAGGATTGCGTGCGAGGTATGCGTTAAGCTCGCTGCGCAGGCTTTCCAGTTGCGACGTGATGGCACCATGTGCTGAGGCCGGATTCTCCGCACCGTAGAGAAGCTTCTG
CACTGTCAGGCCGTGCATCACCTCGTGCAGCAGAATTTGCGGATTATCGATCTGCGTCTGGTTCATGTGAACCTTGTGCGTATTCGGCTCGTAGAACGAACGATCACCAAGCTCACCCGCAAGGCGGCGCATTTCACTCACCTGCACAGGCA
GCGACGCCAATGCGTCAGGTTGGTCCTCCAGAACCTGTTTAATCATCGGCCCAAAAGTGGGGTCATTAGATACCTTCTGCATCGCGGCGTACGCATCCGTCTGGTAGCGTGGCGACACAATCCGGTCCGCAATCTCGCTGTGTACCGTGCCC
GTAATCGGGCGAGTAGGTATGGCAGGCTCGGGCTGCGGACGCGACGCGGCCACGTCCGCCTGCTCTGCGACCACCGCACGCTCCGCTGGCGCAGCCTCCCGCTGGAGGGCCGTGGCGGCGCTCGTCAGCTCGGTCGAGGGGTACGCCTC
GTCGGCGGCAACGAAGCCCTTGCCGGGGCGATACAGGGCCGCTGTGGCCGCTCCATTGACCAGTGCATTGGCGATGACTTCCGTATCGGAGATCGCAGCCTGGGTCTGTGCTGCCCGACCCACCGCGAAGTTACCAGCGGCGCTTGTAGC
GGCTCCGAGTACACGGGCAGTACGTACCCCTGCACCTGCTGCTGTCAGGCTCGTGGCGGTGCCAAATGACGCGAGATCGATGGCAAGGTACACTGGGTCTGCGAAGCTCAGGATGCCCGACAGAAACGGATGGTCGCCCATCTGCCGGT
ACAGGCTGCGTTGCTCGTCCAGAGCGTTGGCCCGGTACTGGTACTCTGCCAGCGACTGCGACTTTGCCAGGAACTTGTGCTCGTCCTCACTGAGCTGGAACGGGGTGCCGTTCACATACGGCTTGGGATCGAATTCCGGGTCGGCGTCGAA
GTGGGGCATCGTGGCCCAGTCCCATACGCGGGTAGTGGTCCAGGACTGCACAGCCGCCTTTGCGGCCTGCCATGCGGTAGCCTGTTCGCGCGAGTTCTGCGCAATCAACGACTGCCCCTGTTCTTCCGATGCCGTTCCGCTCGCGATGCCC
GCCTGCGAGACTTGTGCAGACGGGACAATCGGAGCTGCTGCGCGCCCATCGCCGGGAGTGAACTCCGGGACCGGCGTAGCGGGTACTGCTTCCCCGCCGTAGATACGCGGGTCCACATTAACGATGGGCTCTGCCATGTTTCCTCCTTACT
GAGTGCCCCAGGTGCGGGCGTTGGTGATCGAACTCAACATCGAGTCATAATACTGCTTGCGGGCTGAGTGGGCCATGCGGTACTGCGTGGACGCCTCGCTGCTGACAAGAACGCCAACGCTGCTAAGGCTGCTGCTGTGGCCACAACCAA
CCAACGCGCTAAGGAGGCAACTGATGCGCTCAACAAAGCTGCGGATGCTAACCGCGCTTGGGCTGATGAGCCTGTGCCTGCTGACGTTGCAGGGCTGTTCGTCAACGCGAGTGCAGTTCGCGCTCCCTGATCCCACGCTGTACCAGTCCG
ACATCGCAGTCCCCTCGGGTAAGCCTGCTATGACGAACCAAGACCTAGCCCAGCTCTGTATCGACACGCGCACCGCGCTCGAACTGGCTAACGCTGATCGTGCCGCGCTGCGCGCCTGGGCCGAAACCATCCAGAAGGAGAACAAGCAAT
GAGCATCGCAAACCAGACCACGAACGAAGTGTATGACCTCACCGGCCAGATGGAGAACACCCTCAAGGCGCTGCTCGTCTACCGCTCGGACAGTCGCAATCCGGCCCTCGTTACCTCGGCCAATGCCAGCATGGCGGCGCTGAAGACTTT
GCTCGACGCGGCTATCGCGGACGCCACGCCCCCGGCGGCAGGCACCTAAAGCGTCTAATCGCCTCGTGGCGGGTTTCGGCTCGCCAGGGTAGGCAACCATACCAGCCCATGAGCGCGAGCCCGTCTACGGCCCGCCTCGCAAGTCCCAGG
AGGATTCATGGCTTTCACAATCGCGCAGGCGTACGACATCATCCACGTGTCCGCCCGGCTCAGCTCGGCGGCGTACGCCCGCACCCTGACAAACAACCCCAGCGCAGGAATCGTCGCAGACCTCGAAAATCGGGCCGCTGAGACGATCAC
GACCCTGGGCGGTACTGTGGTCCCATCCACCTCTGCCGTCGTCGCAAACGGCGCCTCAGCCAGCGTGAAGAACAGCGCGGGCACCGTCACCATCGCGGGCACGGCCACGGTCGCCTCGGGCAGCCTCACAGGCGTCTCCCTCCCCGCCAC
TGTGGCCCTCGTGAGCAACGCGGGTACTGTCCCTGTGAAGAACAGCGCTGGGTCTACCGTCGCCGCATCTGCTGTCGCAACCGTGGCCGCTGGCCTCGTGACTGGCGTCGCACTCCCGGCGAGCGTAGCAGCACTGCTCACTGGCGGCAC
CGTAACCGTCACTGACGCTAGCAGCTCGCCGAACCTGTCAGCCACTGTCACGGTGTCTGGCGGCGCGGCTACAGCTACGCTGCCCGCTACTGCTGCGGTACTCCAGAATGGCGACCAAGTCACGATCACAAATGCATCGGGCACGACCAGC
GCGACCTTTCCGATCACCGTGGCGAACGGCGTGCCGACCACGCTGACGCTGCCGGATAACCGGGCGCTCGTATCGGGCAACGCGTACACGATCCCAGTCACCGGCACGTACACCACAACGGTTACACCGACCATCACGAACGGCCAGCTC
GTTGGCATTGTACTCAGTTAAGGAGGAAGTATGGCAGCAGCATTTCTGACGCAAACCGTGGATGCACGTACCAAGCTCGCTAACGCGCTCGACAAGGCTGCGGCCCTCGTGCGCGCTAACGTGCAGCATCAACCGGTCGCCTACCAAACG
GACGTAGTTGCTGCGCTCGTCGCAGCTCAGGCTCAACTCACTACGGCGTTGGTGGGTAACAGCTAAGAGGTAGGAGGGTAGACATGCTAGTAGCTAGTGGCTAATGGCGTCTACCCTTAGGGTATAAGGATTGACGAGTGGAAGGCTTA
GGGATTAGGCTGTGGGAGTGGTAACTAGCAATGCCAGTTGAAAAATTTTTGCGAGGCAGTCTCCGACCCGATGGCGCATGCCTTTCCCCCGTAGGCCCGCCTTTGCAACCATCCACGATGTCGGCTAGGAATTCGCGAGGGTCTAGCCTAA
CAGCTACTAGCGTCTAGCCATTCCTCGCTGTCGCCCAGGGTCTGGATGTCGGCGGCGAAGCCTTCGCGGGCCATCTTGCGCAGAGCATGCTTGAGGGCGAGCTGGAGGAACGTCTCATCGTCCTCGTAATGCTCCTTGTGGATCGAGTGCA
GGTACTCTGCCCCGCCCGCCTCTACAGGGTCGCTGGCATCGCTGCGTAGGCGGCGCAGCAGTGCGTCCGGGACCGTCACGCTGCCGGTAAGCTTGATGTCGAAGTTCAGTGTGCGCATTACGCCACCTCAAAGTTGTCCGTGTTGCCGATC
CTGCGCACCTTGACGTTGCTGTACCGGGCGTTCAGGTTGGTCGAGGCATCCATAGCGCCGCTGCGCCAGAGCAGGCCAGTCAGGAGCGGGTTGCTCATGAGTTGGATGGTCTTGTTGTTCGCGAGGTTGTGCGCCACGTGGCCGTACTGT
AGCCGGTGATGCGGGCCGACCCGCTTGGCATGGAAGGCCACGTTGCGCTTTTCGCGGTAGCGCTCCTTGGCCGGATTGTACGGGATCGGCTGCTGTTGCTGGCCGTAGGGCGCAGCCAATGCATCATGCCGGCAAGCTTGACGGAGTGC
GGTATCCAGTCCTTCCGCGATCTTATCGACTTCGTCGTTTGTCGCGAAGTTGGACAGCGCACTAGCCAGCTTGCTCACGACGCGACCGGCACGTTTAAACAGTTCCATGAGTTCTCCTGCGTTGAAGTTGCGTTTAGAAAATTGGCAGTTGG
CCTTGCGTCTACCAGTCAAGTCTACCAAGCAGCCAACTAACTGCTCGATCGGCCAGTAGCAGTAATGTGCCTACTGCAAACGGGAGCACGGCCTGCGCCTCAAGACGTGCGCGCTGGTCCTTGATGGTCTGCTCCTGTTCCACGAGCTTGCT
GTGGTTGAAGCTCCACGCCACATAGCCGCCAATCAGCGCAGCGAACACCACTGCGCCGATCATGAGGTACTGTTCAAACTTCATTTGTCCTCCGCGCCCAGGTCGCGCACGCACATGGCAATCTCTGCCTCGCGGCGCTTCTTGATGCCATT
GTGAATCTTGGTGCCCGGCTGCGTCCAGTTAGCCAGGGCATGGCAGGCGCTACGCGACTTGCCCGCGTTGAGCAAGCGCACATGTGACGGCACCGCGCCTGAGCGCAGTACGCACATGCCGTCCTTTACGCCCTTACGACCGGGACCGAC
GTTGTACGTGAAGTCAGTCCATGCAGCCCACTCGCCCTCAGTCATTGGAACCTTGACACAACTTGCGACGACTCGCATAGCTTCAGCCATAGCCTTCTGCTCCGCAGCATCGCACTGTGCCTTAGTCGCCACTCCGCGCTTCGCCAGCTCGCC
CGTGATCCCGCGACAGATCGTGGGGACTCCCAACGGGTCTAGATAAGTACGCGTCACTTGCGGCCCCTCGAACTGCGTAGCGAGCTGAAATGCGCCGCCCAATCCAAGCAAGGACGCTAGCGCGGTTGCCGCTGTGATCTTCTTCATTACG
TTTGCCTCCGAGGTTGTTGCGCAGCAGGAAGTAGAGCTGCACCAGCAGTACGATGATGGACAGCAGTGCTGCCCACTGTGCAAGTGCTCAGGACAGCCTGCGCCTCAAGACGTGCGCGCTGATCCTTGATGGTCTGCTCCTGTTCCACGAG
CTTGCTGTGGTTGAAGCTCCACGCCACGTAGCCGCCAATCAGCGCAGCGAACACCACTGCGCCGATCATGAGGTACTGTTCAAACTTCATTTGTCCTCCGCGCCCAGGTCGCGCACGCACATGGCAATCTCTGCCTCGCGCCGCTTCTTGAT
GCCATTGTGGATCTTGGTGCCCGGCTGCGTCCAGTTAGCCAGGGCATGGCAGGCGCTACGCGACTTGCCTGCGTTGAGCAAGCGCACGTGTGACGGCACCGCGCCTGAGCGCAGTACGCACATGCCGTCCTTTACGCCCTTGCGACCGGG
ACCGACGTTGTATGTGAAGTCGGTCCATGCCGCCCACTCGCCCTCTGTCATCGGAACCTTGACACAACTTGCGACGACGCGCATGGCGTCAGCCATAGCCTTCTGCTCAGCAGCGTCGCACTGTGCCTTAGTCGCTACTCCGCGCTTCGCCA
GCTCGCCCGTTATCCCGCGACAGATCGTGGGGACTCCCAACGGGTCGAGATAAGTGCGCGTCACTTGCGGCCCCTCGAACTGCGTAGCGAGCTGAAATGCGCCGCCCAATCCAAGCAAGGACGCTAGCGCTGTTGCCGCTGTGATCTTCTT
CATTACGTTTGCCTCCGAGGTTGTTGCGCAGCAGGAAGTAGAGCTGCGCCAGCAGTACGATGATGGACATCAGTGCCAGCGACTACGATTAGTGCGAACGCAATCACCAATGGTGCCATGTTCATGAGAAGTGCCCTACCTTGGTTACTTC
GACCGTCCGCCCTGCGTTCATGGAGTCGCAGACGAGTTGCGCAGCGCGGGCCGTGTCGTGCGGCACGCTACCCCAGCCGCCGGTGTGTGTGTCGAACACGCGCCACGAACCGCCCTTGTACTGCGCCTGATAGCGGTCGTCCGTGATGGT
CGGATCGTTTTGAATCTTGATGTACTGTGCGCCGTTCATGATGCTCCTTACAGGTAGAGTGCTTCGGGTTCGACAAAGAATTCGCGGTTGAAACTGCCCCAACGTTCAGCGTTCGGGCCGAGCAGTCGGCCGTGTTCCCATGCTGGTTCACG
CACACGGATGGGCACGGCGGCAATGGCATCCTGATCGAGATCGAATGCCGCCACGTTGATGCGATGTCGTGCGCCGTACTGCGCCAGTGGCCGTGTGTCCTCCACCACGAGAACAGCGCAGGGTTCGCCTGTCGCGGGGCACTGTTGCG
CACCGTTGTACTGTCGGATGTCGAACCCAGCACCGCGTACCACTCGCTGGATTCGGTCGTCCTCTATGACGGTGCCTGCGGGCTGGCCTGCCGACTTGCTCGGCCTCTTGCCGATGTTGAGAATGTAGATCATAGAGTGCCCATGCGCTTAT
CGTTGCGCGCCGTGTTGCGGTCCGTTTGGCGGGCTCGTTTCTCCAGCTTGCGCAATTGCGGCGACTACGATTAGTGCGAACGCAATCACCAATGGTGCCATGTTCATGAGAAGTGCCCTACCTTGTCGAATTCGATCGTGCGCCCAGCGTTC
ATGGAATCGCACGCAACCTGAGCAGCGCGCGCCGTATCGTGAGGCACGCTGCCCCAGCCGCCGGTGTGGCTGTCGAAAACTCGCCACGAGCCGCCCTTGTACTGCGCTTGATAGCGGTCGTTCGTGATGGTCGGATCGTTTTGAATCTTGA
TGTACTGTGCGCCGTTCATGATGCTCCTTACAGGTAGAGTGCTTCGGGTTCGACAAAGAATTCGCGGTTGAAACTGCCCCAACGTTCAACGTTCGGGCCGAGCAGTCGGCCGTGTTCCCATGCTGGTTCACGCACACGGATGGGCACGGCG
GCAATGGCATCCTGATCGAGATCGAATGCCACCACGTTGATGCGATGTCGTGCGCCGTACTGCGCCAGTGGCCGTGTGTCCTCCACCACGAGTACCGCGCAAGGTTCGCCTGTCGCGGGGCACTGTTGCGCACCGTTGTACTGTCGGATGT
CGAACCCAGCGCCGCGTACCACTCGCTGGATTCGGTCGTCCTCTATGACGGTGCCTGCGGGCTGGCCTGCCGACTTGCTCGGCCGCTTACCGATGTTGAGAATGTAGATCATAGAGCACCTGTGCGCTTATCGTTGCGCGCCGTGTTGCGG
TCCGCTTGGCGGGCTCGTTTCTCCAGTTTGCGCAGTTGAGCGTAGTAGCCACAATCCCATAGCGCGCAGCGGCATTAGCGTATTCTGTTGCTTGCCACAGGCCCGAGGATGCGAGGCCCACCATCTGAGTAACTGCCTGGACTTTGCGCAG
CCCGTCTGCTACCCGCTCACCAACTGGTTGCCCGCGCAACGCCGCAATTACGTTGTCGAACAAGTCAGCAGCCTCTTGACGCTCTGCGGGGTTTTCGATGCTGTGCATCCAAGTACGGCGCAAGTTATCGATGTCCGTGTTGGTCTTAAGGC
CCACCCTTGCAAGGCTAGCAGTGCCCGCTGCATTGTCGAGATAGCTGTCCAGGTTCCGGGTAAGGTTCCCATCCAGAAGATCAACGATGGACACGCGGCTATTGCCCACTTGCGTGCTAGTTAGCATGTCCATTTCAATGCGATCGTAGTAG
CCACAAGCCCATAGCGCGCAGCGGCATTAGCGTATTCTGTTGCTTGCCACAGGCCCGAGGATGCGAGTCCTACCATCTGAGTAACTGCCTGGACTTTGCGCAGTCCGTCTGCCACTCGCTCACCAACTGGTTGACCGCGCAACGACGCAATT
ACGTTGTCGAACAAGTCAGCAGCCTCTTGCCGTTCTGCGGGATTTTCGATACTGTGCATCCAGGTACGGCGTAAGTTATCGATGTCCGTGTTGGTCTTAAGGCCCACCCTTGCAAGGCTAGCAGTGCCCGCTGCATTGTCGAGATAGCTGTC
CAGGTTCCGGGTAAGGTTCCCATCCAGAAGATCAACGATCGACACTCGGCTATTGCCAACTTGTGTGCTAGTCAGCATGTCCATTTCAATGCGGTCGCGTCGGCTATCGTCTCGCCCCAGCGGCCGTGACGGTAAGCATGCCGCAGCGCGT
CGCCGCTCGCCGGCTGGCTACCGAGCCGAAGGCGGAGATCGCCCATCGTGTCGAGGGCTTCGCCGCCGATGCCGAGATTCCTAGCTTCGGTGAGTCCGACACGCTGGAACAGGCCGAAGCCTAACCCCTTTCAACCAACCCATAGGAGAT
TTACATGCCCATCGTCAACCCGACCCTCCCGCAAACCGGAATCGACCTAGCCGCCGCCACTGCCCAGGGCGCTGCTCAACTTCAAGCCGTTCTGCCGGCCGTACAGGCCGCACAAGCGGCTGTCGCCCCGCGTCGGCTATCGTCTCGCCCCA
GCGGCCGTGACCGTAAGCATGCCGCAGCGCGTCGCCGCTCGCCGGCTGGCTACCGAGCCGAAGGCGGAGATCGCCCATCGTGTCGAGGGCTTCGCCGCCGATGCCGAGACTCCTAGCTTCGGTGAGTCCGACACGCTGGAACAGGCCGA
AGCTTAACCCCTTTCAACCAACCCATAGGAGATTTACATGCCCATCGTCAACCCGACCCTCCCGCAAACCGGAATCGACCTCGCCGCCGCCACTGCCCAGGGCGCTGCTCAACTTCAAGCCGTTCTGCCGGCCGTACAGGCCGCACAAGCGG
CTGTCGCAGCCCAGGTCGCAGCCCAGGTAGTGCCTCGCA